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An antibody raised against a conserved sequence of the prion protein recognizes pathological isoforms in human and animal prion diseases, including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy.
Piccardo P, Langeveld JP, Hill AF, Dlouhy SR, Young K, Giaccone G, Rossi G, Bugiani M, Bugiani O, Meloen RH, Collinge J, Tagliavini F, Ghetti B. Piccardo P, et al. Am J Pathol. 1998 Jun;152(6):1415-20. Am J Pathol. 1998. PMID: 9626045 Free PMC article.
Prion protein amyloidosis.
Ghetti B, Piccardo P, Frangione B, Bugiani O, Giaccone G, Young K, Prelli F, Farlow MR, Dlouhy SR, Tagliavini F. Ghetti B, et al. Among authors: piccardo p. Brain Pathol. 1996 Apr;6(2):127-45. doi: 10.1111/j.1750-3639.1996.tb00796.x. Brain Pathol. 1996. PMID: 8737929 Review.
Hereditary prion protein amyloidoses.
Ghetti B, Tagliavini F, Takao M, Bugiani O, Piccardo P. Ghetti B, et al. Among authors: piccardo p. Clin Lab Med. 2003 Mar;23(1):65-85, viii. doi: 10.1016/s0272-2712(02)00064-1. Clin Lab Med. 2003. PMID: 12733425 Review.
Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP.
Ghetti B, Piccardo P, Spillantini MG, Ichimiya Y, Porro M, Perini F, Kitamoto T, Tateishi J, Seiler C, Frangione B, Bugiani O, Giaccone G, Prelli F, Goedert M, Dlouhy SR, Tagliavini F. Ghetti B, et al. Among authors: piccardo p. Proc Natl Acad Sci U S A. 1996 Jan 23;93(2):744-8. doi: 10.1073/pnas.93.2.744. Proc Natl Acad Sci U S A. 1996. PMID: 8570627 Free PMC article.
Phenotypic variability of Gerstmann-Sträussler-Scheinker disease is associated with prion protein heterogeneity.
Piccardo P, Dlouhy SR, Lievens PM, Young K, Bird TD, Nochlin D, Dickson DW, Vinters HV, Zimmerman TR, Mackenzie IR, Kish SJ, Ang LC, De Carli C, Pocchiari M, Brown P, Gibbs CJ Jr, Gajdusek DC, Bugiani O, Ironside J, Tagliavini F, Ghetti B. Piccardo P, et al. J Neuropathol Exp Neurol. 1998 Oct;57(10):979-88. doi: 10.1097/00005072-199810000-00010. J Neuropathol Exp Neurol. 1998. PMID: 9786248
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