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The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic.
Tombes RM, Auer KL, Mikkelsen R, Valerie K, Wymann MP, Marshall CJ, McMahon M, Dent P. Tombes RM, et al. Among authors: mikkelsen r. Biochem J. 1998 Mar 15;330 ( Pt 3)(Pt 3):1451-60. doi: 10.1042/bj3301451. Biochem J. 1998. PMID: 9494119 Free PMC article.
Ionizing radiation stimulates existing signal transduction pathways involving the activation of epidermal growth factor receptor and ERBB-3, and changes of intracellular calcium in A431 human squamous carcinoma cells.
Todd DG, Mikkelsen RB, Rorrer WK, Valerie K, Schmidt-Ullrich RK. Todd DG, et al. Among authors: mikkelsen rb. J Recept Signal Transduct Res. 1999 Nov;19(6):885-908. doi: 10.3109/10799899909038430. J Recept Signal Transduct Res. 1999. PMID: 10533979
Signal transduction and cellular radiation responses.
Schmidt-Ullrich RK, Dent P, Grant S, Mikkelsen RB, Valerie K. Schmidt-Ullrich RK, et al. Among authors: mikkelsen rb. Radiat Res. 2000 Mar;153(3):245-57. doi: 10.1667/0033-7587(2000)153[0245:stacrr]2.0.co;2. Radiat Res. 2000. PMID: 10669545 Review.
208 results