Nienhuis AW - Search Results

1

Targeted integration of a recombinant globin gene adeno-associated viral vector into human chromosome 19.

Bertran J, Yang Y, Hargrove P, Vanin EF, Nienhuis AW. Bertran J, et al. Among authors: nienhuis aw. Ann N Y Acad Sci. 1998 Jun 30;850:163-77. doi: 10.1111/j.1749-6632.1998.tb10473.x. Ann N Y Acad Sci. 1998. PMID: 9668538

2

Recombinant adeno-associated virus-mediated high-efficiency, transient expression of the murine cationic amino acid transporter (ecotropic retroviral receptor) permits stable transduction of human HeLa cells by ecotropic retroviral vectors.

Bertran J, Miller JL, Yang Y, Fenimore-Justman A, Rueda F, Vanin EF, Nienhuis AW. Bertran J, et al. Among authors: nienhuis aw. J Virol. 1996 Oct;70(10):6759-66. doi: 10.1128/JVI.70.10.6759-6766.1996. J Virol. 1996. PMID: 8794313 Free PMC article.

3

High-level globin gene expression mediated by a recombinant adeno-associated virus genome that contains the 3' gamma globin gene regulatory element and integrates as tandem copies in erythroid cells.

Hargrove PW, Vanin EF, Kurtzman GJ, Nienhuis AW. Hargrove PW, et al. Among authors: nienhuis aw. Blood. 1997 Mar 15;89(6):2167-75. Blood. 1997. PMID: 9058741 Free article.

4

Gene transfer into hematopoietic cells.

Nienhuis AW, Bertran J, Hargrove P, Vanin E, Yang Y. Nienhuis AW, et al. Stem Cells. 1997;15 Suppl 1:123-34. doi: 10.1002/stem.5530150816. Stem Cells. 1997. PMID: 9368332 Review.

5

Efficient gene transfer into human cord blood CD34+ cells and the CD34+CD38- subset using highly purified recombinant adeno-associated viral vector preparations that are free of helper virus and wild-type AAV.

Nathwani AC, Hanawa H, Vandergriff J, Kelly P, Vanin EF, Nienhuis AW. Nathwani AC, et al. Among authors: nienhuis aw. Gene Ther. 2000 Feb;7(3):183-95. doi: 10.1038/sj.gt.3301068. Gene Ther. 2000. PMID: 10694794

6

Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human blood.

Hanawa H, Kelly PF, Nathwani AC, Persons DA, Vandergriff JA, Hargrove P, Vanin EF, Nienhuis AW. Hanawa H, et al. Among authors: nienhuis aw. Mol Ther. 2002 Mar;5(3):242-51. doi: 10.1006/mthe.2002.0549. Mol Ther. 2002. PMID: 11863413 Free article.

7

The degree of phenotypic correction of murine beta -thalassemia intermedia following lentiviral-mediated transfer of a human gamma-globin gene is influenced by chromosomal position effects and vector copy number.

Persons DA, Hargrove PW, Allay ER, Hanawa H, Nienhuis AW. Persons DA, et al. Among authors: nienhuis aw. Blood. 2003 Mar 15;101(6):2175-83. doi: 10.1182/blood-2002-07-2211. Epub 2002 Oct 31. Blood. 2003. PMID: 12411297 Free article.

8

Extended beta-globin locus control region elements promote consistent therapeutic expression of a gamma-globin lentiviral vector in murine beta-thalassemia.

Hanawa H, Hargrove PW, Kepes S, Srivastava DK, Nienhuis AW, Persons DA. Hanawa H, et al. Among authors: nienhuis aw. Blood. 2004 Oct 15;104(8):2281-90. doi: 10.1182/blood-2004-03-0863. Epub 2004 Jun 15. Blood. 2004. PMID: 15198957 Free article.

9

The regulatory element 3' to the A gamma-globin gene binds to the nuclear matrix and interacts with special A-T-rich binding protein 1 (SATB1), an SAR/MAR-associating region DNA binding protein.

Cunningham JM, Purucker ME, Jane SM, Safer B, Vanin EF, Ney PA, Lowrey CH, Nienhuis AW. Cunningham JM, et al. Among authors: nienhuis aw. Blood. 1994 Aug 15;84(4):1298-308. Blood. 1994. PMID: 8049444 Free article.

10

Inducible, high-level production of infectious murine leukemia retroviral vector particles pseudotyped with vesicular stomatitis virus G envelope protein.

Yang Y, Vanin EF, Whitt MA, Fornerod M, Zwart R, Schneiderman RD, Grosveld G, Nienhuis AW. Yang Y, et al. Among authors: nienhuis aw. Hum Gene Ther. 1995 Sep;6(9):1203-13. doi: 10.1089/hum.1995.6.9-1203. Hum Gene Ther. 1995. PMID: 8527479

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