Baumeister R - Search Results

1

Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing.

Baumeister R, Leimer U, Zweckbronner I, Jakubek C, Grünberg J, Haass C. Baumeister R, et al. Genes Funct. 1997 Apr;1(2):149-59. doi: 10.1046/j.1365-4624.1997.00012.x. Genes Funct. 1997. PMID: 9680315

2

Proteolytic processing of Alzheimer's disease associated proteins.

Haass C, Grünberg J, Capell A, Wild-Bode C, Leimer U, Walter J, Yamazaki T, Ihara I, Zweckbronner I, Jakubek C, Baumeister R. Haass C, et al. Among authors: baumeister r. J Neural Transm Suppl. 1998;53:159-67. doi: 10.1007/978-3-7091-6467-9_14. J Neural Transm Suppl. 1998. PMID: 9700654 Review.

3

What do we learn from a few familial Alzheimer's disease cases?

Haass C, Baumeister R. Haass C, et al. Among authors: baumeister r. J Neural Transm Suppl. 1998;54:137-45. doi: 10.1007/978-3-7091-7508-8_13. J Neural Transm Suppl. 1998. PMID: 9850922 Review.

4

The biological and pathological function of the presenilin-1 Deltaexon 9 mutation is independent of its defect to undergo proteolytic processing.

Steiner H, Romig H, Grim MG, Philipp U, Pesold B, Citron M, Baumeister R, Haass C. Steiner H, et al. Among authors: baumeister r. J Biol Chem. 1999 Mar 19;274(12):7615-8. doi: 10.1074/jbc.274.12.7615. J Biol Chem. 1999. PMID: 10075646 Free article.

5

A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling.

Steiner H, Duff K, Capell A, Romig H, Grim MG, Lincoln S, Hardy J, Yu X, Picciano M, Fechteler K, Citron M, Kopan R, Pesold B, Keck S, Baader M, Tomita T, Iwatsubo T, Baumeister R, Haass C. Steiner H, et al. Among authors: baumeister r. J Biol Chem. 1999 Oct 1;274(40):28669-73. doi: 10.1074/jbc.274.40.28669. J Biol Chem. 1999. PMID: 10497236 Free article.

6

The biological and pathological function of presenilin proteins--simple cell systems and a worm in Alzheimer's disease research.

Haass C, Baumeister R. Haass C, et al. Among authors: baumeister r. Eur Arch Psychiatry Clin Neurosci. 1999;249 Suppl 3:23-7. doi: 10.1007/pl00014169. Eur Arch Psychiatry Clin Neurosci. 1999. PMID: 10654096 Review.

7

Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch.

Capell A, Steiner H, Romig H, Keck S, Baader M, Grim MG, Baumeister R, Haass C. Capell A, et al. Among authors: baumeister r. Nat Cell Biol. 2000 Apr;2(4):205-11. doi: 10.1038/35008626. Nat Cell Biol. 2000. PMID: 10783238

8

Separation of presenilin function in amyloid beta-peptide generation and endoproteolysis of Notch.

Kulic L, Walter J, Multhaup G, Teplow DB, Baumeister R, Romig H, Capell A, Steiner H, Haass C. Kulic L, et al. Among authors: baumeister r. Proc Natl Acad Sci U S A. 2000 May 23;97(11):5913-8. doi: 10.1073/pnas.100049897. Proc Natl Acad Sci U S A. 2000. PMID: 10811883 Free PMC article.

9

A loss of function mutant of the presenilin homologue SEL-12 undergoes aberrant endoproteolysis in Caenorhabditis elegans and increases abeta 42 generation in human cells.

Okochi M, Eimer S, Bottcher A, Baumeister R, Romig H, Walter J, Capell A, Steiner H, Haass C. Okochi M, et al. Among authors: baumeister r. J Biol Chem. 2000 Dec 29;275(52):40925-32. doi: 10.1074/jbc.M005254200. J Biol Chem. 2000. PMID: 11013240 Free article.

10

Caspase-mediated cleavage is not required for the activity of presenilins in amyloidogenesis and NOTCH signaling.

Brockhaus M, Grünberg J, Röhrig S, Loetscher H, Wittenburg N, Baumeister R, Jacobsen H, Haass C. Brockhaus M, et al. Among authors: baumeister r. Neuroreport. 1998 May 11;9(7):1481-6. doi: 10.1097/00001756-199805110-00043. Neuroreport. 1998. PMID: 9631452

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