Rose-John S - Search Results

1

The membrane proximal cytokine receptor domain of the human interleukin-6 receptor is sufficient for ligand binding but not for gp130 association.

Ozbek S, Grötzinger J, Krebs B, Fischer M, Wollmer A, Jostock T, Müllberg J, Rose-John S. Ozbek S, et al. J Biol Chem. 1998 Aug 14;273(33):21374-9. doi: 10.1074/jbc.273.33.21374. J Biol Chem. 1998. PMID: 9694899 Free article.

2

Protein kinase C activity is rate limiting for shedding of the interleukin-6 receptor.

Müllberg J, Schooltink H, Stoyan T, Heinrich PC, Rose-John S. Müllberg J, et al. Biochem Biophys Res Commun. 1992 Dec 15;189(2):794-800. doi: 10.1016/0006-291x(92)92272-y. Biochem Biophys Res Commun. 1992. PMID: 1335247

3

Structural and functional studies on the human interleukin-6 receptor. Binding, cross-linking, internalization, and degradation of interleukin-6 by fibroblasts transfected with human interleukin-6-receptor cDNA.

Rose-John S, Hipp E, Lenz D, Legrés LG, Korr H, Hirano T, Kishimoto T, Heinrich PC. Rose-John S, et al. J Biol Chem. 1991 Feb 25;266(6):3841-6. J Biol Chem. 1991. PMID: 1995637 Free article.

4

Structure-function analysis of human interleukin-6. Evidence for the involvement of the carboxy-terminus in function.

Krüttgen A, Rose-John S, Möller C, Wroblowski B, Wollmer A, Müllberg J, Hirano T, Kishimoto T, Heinrich PC. Krüttgen A, et al. FEBS Lett. 1990 Mar 26;262(2):323-6. doi: 10.1016/0014-5793(90)80219-9. FEBS Lett. 1990. PMID: 2335213 Free article.

5

Identification of two novel regions of human IL-6 responsible for receptor binding and signal transduction.

Ehlers M, Grötzinger J, deHon FD, Müllberg J, Brakenhoff JP, Liu J, Wollmer A, Rose-John S. Ehlers M, et al. J Immunol. 1994 Aug 15;153(4):1744-53. J Immunol. 1994. PMID: 7519211

6

A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor.

Müllberg J, Durie FH, Otten-Evans C, Alderson MR, Rose-John S, Cosman D, Black RA, Mohler KM. Müllberg J, et al. J Immunol. 1995 Dec 1;155(11):5198-205. J Immunol. 1995. PMID: 7594530

7

Leucine-58 in the putative 5th helical region of human interleukin (IL)-6 is important for activation of the IL-6 signal transducer, gp130.

de Hon FD, Klaasse Bos HK, Ebeling SB, Grötzinger J, Kurapkat G, Rose-John S, Aarden LA, Brakenhoff JP. de Hon FD, et al. FEBS Lett. 1995 Aug 7;369(2-3):187-91. doi: 10.1016/0014-5793(95)00741-q. FEBS Lett. 1995. PMID: 7649255 Free article.

8

The soluble interleukin-6 receptor.

Rose-John S, Ehlers M, Grötzinger J, Müllberg J. Rose-John S, et al. Ann N Y Acad Sci. 1995 Jul 21;762:207-20; discussion 220-1. Ann N Y Acad Sci. 1995. PMID: 7668529 No abstract available.

9

Residues 77-95 of the human interleuken-6 protein are responsible for receptor binding and residues 41-56 for signal transduction.

Ehlers M, Grötzinger J, de Hon FD, Müllberg J, Brakenhoff JP, Wollmer A, Rose-John S. Ehlers M, et al. Ann N Y Acad Sci. 1995 Jul 21;762:400-2. doi: 10.1111/j.1749-6632.1995.tb32347.x. Ann N Y Acad Sci. 1995. PMID: 7668541 No abstract available.

10

A region within the cytoplasmic domain of the interleukin-6 signal transducer gp130 important for ligand-induced endocytosis of the IL-6 receptor.

Dittrich E, Gerhartz C, Rose-John S, Müllberg J, Stoyan T, Heinrich PC, Graeve L. Dittrich E, et al. Ann N Y Acad Sci. 1995 Jul 21;762:410-2. doi: 10.1111/j.1749-6632.1995.tb32350.x. Ann N Y Acad Sci. 1995. PMID: 7668544 No abstract available.

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