Opgenorth TJ - Search Results

1

Pyrrolidine-3-carboxylic acids as endothelin antagonists. 3. Discovery of a potent, 2-nonaryl, highly selective ETA antagonist (A-216546).

Liu G, Henry KJ Jr, Szczepankiewicz BG, Winn M, Kozmina NS, Boyd SA, Wasicak J, von Geldern TW, Wu-Wong JR, Chiou WJ, Dixon DB, Nguyen B, Marsh KC, Opgenorth TJ. Liu G, et al. Among authors: opgenorth tj. J Med Chem. 1998 Aug 13;41(17):3261-75. doi: 10.1021/jm980217s. J Med Chem. 1998. PMID: 9703472

2

Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: in vitro studies.

Wu-Wong JR, Dixon DB, Chiou WJ, Sorensen BK, Liu G, Jae HS, Tasker A, von Geldern TW, Winn M, Opgenorth TJ. Wu-Wong JR, et al. Among authors: opgenorth tj. Clin Sci (Lond). 2002 Aug;103 Suppl 48:107S-111S. doi: 10.1042/CS103S107S. Clin Sci (Lond). 2002. PMID: 12193066

3

Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: ex vivo and in vivo studies.

Wessale JL, Adler AL, Novosad EI, Calzadilla SV, Dayton BD, Marsh KC, Winn M, Jae HS, von Geldern TW, Opgenorth TJ, Wu-Wong JR. Wessale JL, et al. Among authors: opgenorth tj. Clin Sci (Lond). 2002 Aug;103 Suppl 48:112S-117S. doi: 10.1042/CS103S112S. Clin Sci (Lond). 2002. PMID: 12193067

4

Endothelin receptor in human astrocytoma U373MG cells: binding, dissociation, receptor internalization.

Wu-Wong JR, Chiou WJ, Magnuson SR, Opgenorth TJ. Wu-Wong JR, et al. Among authors: opgenorth tj. J Pharmacol Exp Ther. 1995 Jul;274(1):499-507. J Pharmacol Exp Ther. 1995. PMID: 7616437

5

Endothelin receptors in human smooth muscle cells: antagonist potency differs on agonist-evoked responses.

Wu-Wong JR, Chiou WJ, Huang ZJ, Vidal MJ, Opgenorth TJ. Wu-Wong JR, et al. Among authors: opgenorth tj. Am J Physiol. 1994 Nov;267(5 Pt 1):C1185-95. doi: 10.1152/ajpcell.1994.267.5.C1185. Am J Physiol. 1994. PMID: 7977682

6

Endothelin receptor agonists and antagonists exhibit different dissociation characteristics.

Wu-Wong JR, Chiou WJ, Magnuson SR, Opgenorth TJ. Wu-Wong JR, et al. Among authors: opgenorth tj. Biochim Biophys Acta. 1994 Nov 10;1224(2):288-94. doi: 10.1016/0167-4889(94)90202-x. Biochim Biophys Acta. 1994. PMID: 7981244

7

Endothelin receptor antagonists exhibit diminishing potency following incubation with agonist.

Wu-Wong JR, Chiou WJ, Naugles KE Jr, Opgenorth TJ. Wu-Wong JR, et al. Among authors: opgenorth tj. Life Sci. 1994;54(22):1727-34. doi: 10.1016/0024-3205(94)00613-x. Life Sci. 1994. PMID: 8177014

8

Potent and selective inhibitors of an aspartyl protease-like endothelin converting enzyme identified in rat lung.

Shiosaki K, Tasker AS, Sullivan GM, Sorensen BK, von Geldern TW, Wu-Wong JR, Marselle CA, Opgenorth TJ. Shiosaki K, et al. Among authors: opgenorth tj. J Med Chem. 1993 Feb 19;36(4):468-78. doi: 10.1021/jm00056a007. J Med Chem. 1993. PMID: 8474103

9

Dissociation characteristics of endothelin ETA receptor agonists and antagonists.

Wu-Wong JR, Chiou WJ, Dixon DB, Opgenorth TJ. Wu-Wong JR, et al. Among authors: opgenorth tj. J Cardiovasc Pharmacol. 1995;26 Suppl 3:S380-4. J Cardiovasc Pharmacol. 1995. PMID: 8587421

10

Pharmacological characterization of A-127722: an orally active and highly potent ETA-selective receptor antagonist.

Opgenorth TJ, Adler AL, Calzadilla SV, Chiou WJ, Dayton BD, Dixon DB, Gehrke LJ, Hernandez L, Magnuson SR, Marsh KC, Novosad EI, Von Geldern TW, Wessale JL, Winn M, Wu-Wong JR. Opgenorth TJ, et al. J Pharmacol Exp Ther. 1996 Feb;276(2):473-81. J Pharmacol Exp Ther. 1996. PMID: 8632312

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

127 results

Search Page

Filters