Simon MC - Search Results

1

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription.

Chandel NS, Maltepe E, Goldwasser E, Mathieu CE, Simon MC, Schumacker PT. Chandel NS, et al. Among authors: simon mc. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11715-20. doi: 10.1073/pnas.95.20.11715. Proc Natl Acad Sci U S A. 1998. PMID: 9751731 Free PMC article.

2

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing.

Guzy RD, Hoyos B, Robin E, Chen H, Liu L, Mansfield KD, Simon MC, Hammerling U, Schumacker PT. Guzy RD, et al. Among authors: simon mc. Cell Metab. 2005 Jun;1(6):401-8. doi: 10.1016/j.cmet.2005.05.001. Cell Metab. 2005. PMID: 16054089 Free article.

3

Cellular adaptation to hypoxia through hypoxia inducible factors and beyond.

Lee P, Chandel NS, Simon MC. Lee P, et al. Among authors: simon mc. Nat Rev Mol Cell Biol. 2020 May;21(5):268-283. doi: 10.1038/s41580-020-0227-y. Epub 2020 Mar 6. Nat Rev Mol Cell Biol. 2020. PMID: 32144406 Free PMC article. Review.

4

c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1.

Brunelle JK, Santore MT, Budinger GR, Tang Y, Barrett TA, Zong WX, Kandel E, Keith B, Simon MC, Thompson CB, Hay N, Chandel NS. Brunelle JK, et al. Among authors: simon mc. J Biol Chem. 2004 Feb 6;279(6):4305-12. doi: 10.1074/jbc.M312241200. Epub 2003 Nov 19. J Biol Chem. 2004. PMID: 14627695 Free article.

5

Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

Maltepe E, Schmidt JV, Baunoch D, Bradfield CA, Simon MC. Maltepe E, et al. Among authors: simon mc. Nature. 1997 Mar 27;386(6623):403-7. doi: 10.1038/386403a0. Nature. 1997. PMID: 9121557

6

Oxygen, genes, and development: an analysis of the role of hypoxic gene regulation during murine vascular development.

Maltepe E, Simon MC. Maltepe E, et al. Among authors: simon mc. J Mol Med (Berl). 1998 May;76(6):391-401. doi: 10.1007/s001090050231. J Mol Med (Berl). 1998. PMID: 9625296 Review.

7

Multilineage embryonic hematopoiesis requires hypoxic ARNT activity.

Adelman DM, Maltepe E, Simon MC. Adelman DM, et al. Among authors: simon mc. Genes Dev. 1999 Oct 1;13(19):2478-83. doi: 10.1101/gad.13.19.2478. Genes Dev. 1999. PMID: 10521392 Free PMC article.

8

HIF-1 is essential for multilineage hematopoiesis in the embryo.

Adelman DM, Maltepe E, Simon MC. Adelman DM, et al. Among authors: simon mc. Adv Exp Med Biol. 2000;475:275-84. doi: 10.1007/0-306-46825-5_26. Adv Exp Med Biol. 2000. PMID: 10849668 No abstract available.

9

The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia.

Maltepe E, Keith B, Arsham AM, Brorson JR, Simon MC. Maltepe E, et al. Among authors: simon mc. Biochem Biophys Res Commun. 2000 Jun 24;273(1):231-8. doi: 10.1006/bbrc.2000.2928. Biochem Biophys Res Commun. 2000. PMID: 10873592

10

Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses.

Adelman DM, Gertsenstein M, Nagy A, Simon MC, Maltepe E. Adelman DM, et al. Among authors: simon mc. Genes Dev. 2000 Dec 15;14(24):3191-203. doi: 10.1101/gad.853700. Genes Dev. 2000. PMID: 11124810 Free PMC article.

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