Friend SH - Search Results

1

Drug target validation and identification of secondary drug target effects using DNA microarrays.

Marton MJ, DeRisi JL, Bennett HA, Iyer VR, Meyer MR, Roberts CJ, Stoughton R, Burchard J, Slade D, Dai H, Bassett DE Jr, Hartwell LH, Brown PO, Friend SH. Marton MJ, et al. Among authors: friend sh. Nat Med. 1998 Nov;4(11):1293-301. doi: 10.1038/3282. Nat Med. 1998. PMID: 9809554

2

Widespread aneuploidy revealed by DNA microarray expression profiling.

Hughes TR, Roberts CJ, Dai H, Jones AR, Meyer MR, Slade D, Burchard J, Dow S, Ward TR, Kidd MJ, Friend SH, Marton MJ. Hughes TR, et al. Among authors: friend sh. Nat Genet. 2000 Jul;25(3):333-7. doi: 10.1038/77116. Nat Genet. 2000. PMID: 10888885

3

Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer.

Hughes TR, Mao M, Jones AR, Burchard J, Marton MJ, Shannon KW, Lefkowitz SM, Ziman M, Schelter JM, Meyer MR, Kobayashi S, Davis C, Dai H, He YD, Stephaniants SB, Cavet G, Walker WL, West A, Coffey E, Shoemaker DD, Stoughton R, Blanchard AP, Friend SH, Linsley PS. Hughes TR, et al. Among authors: friend sh. Nat Biotechnol. 2001 Apr;19(4):342-7. doi: 10.1038/86730. Nat Biotechnol. 2001. PMID: 11283592

4

Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles.

Roberts CJ, Nelson B, Marton MJ, Stoughton R, Meyer MR, Bennett HA, He YD, Dai H, Walker WL, Hughes TR, Tyers M, Boone C, Friend SH. Roberts CJ, et al. Among authors: friend sh. Science. 2000 Feb 4;287(5454):873-80. doi: 10.1126/science.287.5454.873. Science. 2000. PMID: 10657304

5

Functional discovery via a compendium of expression profiles.

Hughes TR, Marton MJ, Jones AR, Roberts CJ, Stoughton R, Armour CD, Bennett HA, Coffey E, Dai H, He YD, Kidd MJ, King AM, Meyer MR, Slade D, Lum PY, Stepaniants SB, Shoemaker DD, Gachotte D, Chakraburtty K, Simon J, Bard M, Friend SH. Hughes TR, et al. Among authors: friend sh. Cell. 2000 Jul 7;102(1):109-26. doi: 10.1016/s0092-8674(00)00015-5. Cell. 2000. PMID: 10929718 Free article.

6

The magic of microarrays.

Friend SH, Stoughton RB. Friend SH, et al. Sci Am. 2002 Feb;286(2):44-9, 53. doi: 10.1038/scientificamerican0202-44. Sci Am. 2002. PMID: 11828700 No abstract available.

7

How molecular profiling could revolutionize drug discovery.

Stoughton RB, Friend SH. Stoughton RB, et al. Among authors: friend sh. Nat Rev Drug Discov. 2005 Apr;4(4):345-50. doi: 10.1038/nrd1696. Nat Rev Drug Discov. 2005. PMID: 15789121 Review.

8

Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae.

Simon JA, Szankasi P, Nguyen DK, Ludlow C, Dunstan HM, Roberts CJ, Jensen EL, Hartwell LH, Friend SH. Simon JA, et al. Among authors: friend sh. Cancer Res. 2000 Jan 15;60(2):328-33. Cancer Res. 2000. PMID: 10667584

9

Genetics of gene expression surveyed in maize, mouse and man.

Schadt EE, Monks SA, Drake TA, Lusis AJ, Che N, Colinayo V, Ruff TG, Milligan SB, Lamb JR, Cavet G, Linsley PS, Mao M, Stoughton RB, Friend SH. Schadt EE, et al. Among authors: friend sh. Nature. 2003 Mar 20;422(6929):297-302. doi: 10.1038/nature01434. Nature. 2003. PMID: 12646919

10

Integrating genetic approaches into the discovery of anticancer drugs.

Hartwell LH, Szankasi P, Roberts CJ, Murray AW, Friend SH. Hartwell LH, et al. Among authors: friend sh. Science. 1997 Nov 7;278(5340):1064-8. doi: 10.1126/science.278.5340.1064. Science. 1997. PMID: 9353181 Review.

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