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Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes.
Lippa CF, Fujiwara H, Mann DM, Giasson B, Baba M, Schmidt ML, Nee LE, O'Connell B, Pollen DA, St George-Hyslop P, Ghetti B, Nochlin D, Bird TD, Cairns NJ, Lee VM, Iwatsubo T, Trojanowski JQ. Lippa CF, et al. Am J Pathol. 1998 Nov;153(5):1365-70. doi: 10.1016/s0002-9440(10)65722-7. Am J Pathol. 1998. PMID: 9811326 Free PMC article.
Distinguishable effects of presenilin-1 and APP717 mutations on amyloid plaque deposition.
Ishii K, Lippa C, Tomiyama T, Miyatake F, Ozawa K, Tamaoka A, Hasegawa T, Fraser PE, Shoji S, Nee LE, Pollen DA, St George-Hyslop PH, Ii K, Ohtake T, Kalaria RN, Rossor MN, Lantos PL, Cairns NJ, Farrer LA, Mori H. Ishii K, et al. Neurobiol Aging. 2001 May-Jun;22(3):367-76. doi: 10.1016/s0197-4580(01)00216-0. Neurobiol Aging. 2001. PMID: 11378241
Presenilin-1 C410Y Alzheimer disease plaques contain synaptic proteins.
Haleem K, Lippa CF, Smith TW, Kowa H, Wu J, Iwatsubo T. Haleem K, et al. Among authors: lippa cf. Am J Alzheimers Dis Other Demen. 2007 Apr-May;22(2):137-44. doi: 10.1177/1533317506298051. Am J Alzheimers Dis Other Demen. 2007. PMID: 17545141 Free PMC article.
163 results