Chang JC - Search Results

1

Transgenic knockout mice exclusively expressing human hemoglobin S after transfer of a 240-kb betas-globin yeast artificial chromosome: A mouse model of sickle cell anemia.

Chang JC, Lu R, Lin C, Xu SM, Kan YW, Porcu S, Carlson E, Kitamura M, Yang S, Flebbe-Rehwaldt L, Gaensler KM. Chang JC, et al. Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14886-90. doi: 10.1073/pnas.95.25.14886. Proc Natl Acad Sci U S A. 1998. PMID: 9843985 Free PMC article.

2

Fetal gene therapy of alpha-thalassemia in a mouse model.

Han XD, Lin C, Chang J, Sadelain M, Kan YW. Han XD, et al. Proc Natl Acad Sci U S A. 2007 May 22;104(21):9007-11. doi: 10.1073/pnas.0702457104. Epub 2007 May 11. Proc Natl Acad Sci U S A. 2007. PMID: 17496141 Free PMC article.

3

Correction of the sickle cell mutation in embryonic stem cells.

Chang JC, Ye L, Kan YW. Chang JC, et al. Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):1036-40. doi: 10.1073/pnas.0510177103. Epub 2006 Jan 11. Proc Natl Acad Sci U S A. 2006. PMID: 16407095 Free PMC article.

4

High oxygen environment during pregnancy rescues sickle cell anemia mice from prenatal death.

Ye L, Chang JC, Lu R, Kan YW. Ye L, et al. Among authors: chang jc. Blood Cells Mol Dis. 2008 Jul-Aug;41(1):67-72. doi: 10.1016/j.bcmd.2007.12.002. Epub 2008 Jan 22. Blood Cells Mol Dis. 2008. PMID: 18207438

5

Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases.

Ye L, Chang JC, Lin C, Sun X, Yu J, Kan YW. Ye L, et al. Among authors: chang jc. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9826-30. doi: 10.1073/pnas.0904689106. Epub 2009 May 29. Proc Natl Acad Sci U S A. 2009. PMID: 19482945 Free PMC article.

6

Inactivation of mouse alpha-globin gene by homologous recombination: mouse model of hemoglobin H disease.

Chang J, Lu RH, Xu SM, Meneses J, Chan K, Pedersen R, Kan YW. Chang J, et al. Blood. 1996 Sep 1;88(5):1846-51. Blood. 1996. PMID: 8781443 Free article.

7

The human beta globin locus introduced by YAC transfer exhibits a specific and reproducible pattern of developmental regulation in transgenic mice.

Porcu S, Kitamura M, Witkowska E, Zhang Z, Mutero A, Lin C, Chang J, Gaensler KM. Porcu S, et al. Blood. 1997 Dec 1;90(11):4602-9. Blood. 1997. PMID: 9373272 Free article.

8

A 36-base-pair core sequence of locus control region enhances retrovirally transferred human beta-globin gene expression.

Chang JC, Liu D, Kan YW. Chang JC, et al. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):3107-10. doi: 10.1073/pnas.89.7.3107. Proc Natl Acad Sci U S A. 1992. PMID: 1557419 Free PMC article.

9

Dissection of the enhancer activity of beta-globin 5' DNase I-hypersensitive site 2 in transgenic mice.

Liu D, Chang JC, Moi P, Liu W, Kan YW, Curtin PT. Liu D, et al. Among authors: chang jc. Proc Natl Acad Sci U S A. 1992 May 1;89(9):3899-903. doi: 10.1073/pnas.89.9.3899. Proc Natl Acad Sci U S A. 1992. PMID: 1570310 Free PMC article.

10

Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site.

Curtin PT, Liu DP, Liu W, Chang JC, Kan YW. Curtin PT, et al. Among authors: chang jc. Proc Natl Acad Sci U S A. 1989 Sep;86(18):7082-6. doi: 10.1073/pnas.86.18.7082. Proc Natl Acad Sci U S A. 1989. PMID: 2780563 Free PMC article.

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