Checler F - Search Results

1

Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides.

Greenfield JP, Tsai J, Gouras GK, Hai B, Thinakaran G, Checler F, Sisodia SS, Greengard P, Xu H. Greenfield JP, et al. Among authors: checler f. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):742-7. doi: 10.1073/pnas.96.2.742. Proc Natl Acad Sci U S A. 1999. PMID: 9892704 Free PMC article.

2

Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides.

Xu H, Gouras GK, Greenfield JP, Vincent B, Naslund J, Mazzarelli L, Fried G, Jovanovic JN, Seeger M, Relkin NR, Liao F, Checler F, Buxbaum JD, Chait BT, Thinakaran G, Sisodia SS, Wang R, Greengard P, Gandy S. Xu H, et al. Among authors: checler f. Nat Med. 1998 Apr;4(4):447-51. doi: 10.1038/nm0498-447. Nat Med. 1998. PMID: 9546791

3

Unusual phenotypic alteration of beta amyloid precursor protein (betaAPP) maturation by a new Val-715 --> Met betaAPP-770 mutation responsible for probable early-onset Alzheimer's disease.

Ancolio K, Dumanchin C, Barelli H, Warter JM, Brice A, Campion D, Frébourg T, Checler F. Ancolio K, et al. Among authors: checler f. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):4119-24. doi: 10.1073/pnas.96.7.4119. Proc Natl Acad Sci U S A. 1999. PMID: 10097173 Free PMC article.

4

Intraneuronal Abeta42 accumulation in human brain.

Gouras GK, Tsai J, Naslund J, Vincent B, Edgar M, Checler F, Greenfield JP, Haroutunian V, Buxbaum JD, Xu H, Greengard P, Relkin NR. Gouras GK, et al. Among authors: checler f. Am J Pathol. 2000 Jan;156(1):15-20. doi: 10.1016/s0002-9440(10)64700-1. Am J Pathol. 2000. PMID: 10623648 Free PMC article.

5

Mutant presenilin 1 increases the levels of Alzheimer amyloid beta-peptide Abeta42 in late compartments of the constitutive secretory pathway.

Petanceska SS, Seeger M, Checler F, Gandy S. Petanceska SS, et al. Among authors: checler f. J Neurochem. 2000 May;74(5):1878-84. doi: 10.1046/j.1471-4159.2000.0741878.x. J Neurochem. 2000. PMID: 10800930 Free article.

6

Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production.

Benjannet S, Elagoz A, Wickham L, Mamarbachi M, Munzer JS, Basak A, Lazure C, Cromlish JA, Sisodia S, Checler F, Chrétien M, Seidah NG. Benjannet S, et al. Among authors: checler f. J Biol Chem. 2001 Apr 6;276(14):10879-87. doi: 10.1074/jbc.M009899200. Epub 2001 Jan 10. J Biol Chem. 2001. PMID: 11152688 Free article.

7

Human amyloid-beta causes changes in the levels of endothelial protein kinase C and its alpha isoform in vitro.

Pakaski M, Balaspiri L, Checler F, Kasa P. Pakaski M, et al. Among authors: checler f. Neurochem Int. 2002 Dec;41(6):409-14. doi: 10.1016/s0197-0186(02)00026-8. Neurochem Int. 2002. PMID: 12213228

8

Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers.

Gandy S, Simon AJ, Steele JW, Lublin AL, Lah JJ, Walker LC, Levey AI, Krafft GA, Levy E, Checler F, Glabe C, Bilker WB, Abel T, Schmeidler J, Ehrlich ME. Gandy S, et al. Among authors: checler f. Ann Neurol. 2010 Aug;68(2):220-30. doi: 10.1002/ana.22052. Ann Neurol. 2010. PMID: 20641005 Free PMC article.

9

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

Chui DH, Tanahashi H, Ozawa K, Ikeda S, Checler F, Ueda O, Suzuki H, Araki W, Inoue H, Shirotani K, Takahashi K, Gallyas F, Tabira T. Chui DH, et al. Among authors: checler f. Nat Med. 1999 May;5(5):560-4. doi: 10.1038/8438. Nat Med. 1999. PMID: 10229234

10

Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease.

Suh YH, Checler F. Suh YH, et al. Among authors: checler f. Pharmacol Rev. 2002 Sep;54(3):469-525. doi: 10.1124/pr.54.3.469. Pharmacol Rev. 2002. PMID: 12223532 Review.

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