Trapani JA - Search Results

1

Lymphocyte-mediated cytolysis: dual apoptotic mechanisms with overlapping cytoplasmic and nuclear signalling pathways.

Trapani JA, Jans DA. Trapani JA, et al. Results Probl Cell Differ. 1999;23:78-102. Results Probl Cell Differ. 1999. PMID: 9950030 Review. No abstract available.

2

Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis.

Trapani JA, Browne KA, Smyth MJ, Jans DA. Trapani JA, et al. J Biol Chem. 1996 Feb 23;271(8):4127-33. doi: 10.1074/jbc.271.8.4127. J Biol Chem. 1996. PMID: 8626751 Free article.

3

Lymphocyte granule-mediated cell death.

Trapani JA, Jans DA, Sutton VR. Trapani JA, et al. Springer Semin Immunopathol. 1998;19(3):323-43. doi: 10.1007/BF00787229. Springer Semin Immunopathol. 1998. PMID: 9540160 Review. No abstract available.

4

Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction.

Trapani JA, Jans P, Smyth MJ, Froelich CJ, Williams EA, Sutton VR, Jans DA. Trapani JA, et al. Cell Death Differ. 1998 Jun;5(6):488-96. doi: 10.1038/sj.cdd.4400373. Cell Death Differ. 1998. PMID: 10200500

5

A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death.

Trapani JA, Sutton VR, Thia KY, Li YQ, Froelich CJ, Jans DA, Sandrin MS, Browne KA. Trapani JA, et al. J Cell Biol. 2003 Jan 20;160(2):223-33. doi: 10.1083/jcb.200210150. Epub 2003 Jan 21. J Cell Biol. 2003. PMID: 12538642 Free PMC article.

6

Nuclear targeting of the serine protease granzyme A (fragmentin-1).

Jans DA, Briggs LJ, Jans P, Froelich CJ, Parasivam G, Kumar S, Sutton VR, Trapani JA. Jans DA, et al. Among authors: trapani ja. J Cell Sci. 1998 Sep;111 ( Pt 17):2645-54. doi: 10.1242/jcs.111.17.2645. J Cell Sci. 1998. PMID: 9701563

7

Efficient nuclear targeting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent.

Trapani JA, Jans DA, Jans PJ, Smyth MJ, Browne KA, Sutton VR. Trapani JA, et al. J Biol Chem. 1998 Oct 23;273(43):27934-8. doi: 10.1074/jbc.273.43.27934. J Biol Chem. 1998. PMID: 9774406 Free article.

8

Perforin-dependent nuclear targeting of granzymes: A central role in the nuclear events of granule-exocytosis-mediated apoptosis?

Blink EJ, Trapani JA, Jans DA. Blink EJ, et al. Among authors: trapani ja. Immunol Cell Biol. 1999 Jun;77(3):206-15. doi: 10.1046/j.1440-1711.1999.00817.x. Immunol Cell Biol. 1999. PMID: 10361252 Review.

9

Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin.

Browne KA, Blink E, Sutton VR, Froelich CJ, Jans DA, Trapani JA. Browne KA, et al. Among authors: trapani ja. Mol Cell Biol. 1999 Dec;19(12):8604-15. doi: 10.1128/MCB.19.12.8604. Mol Cell Biol. 1999. PMID: 10567584 Free PMC article.

10

Filamin (280-kDa actin-binding protein) is a caspase substrate and is also cleaved directly by the cytotoxic T lymphocyte protease granzyme B during apoptosis.

Browne KA, Johnstone RW, Jans DA, Trapani JA. Browne KA, et al. Among authors: trapani ja. J Biol Chem. 2000 Dec 15;275(50):39262-6. doi: 10.1074/jbc.C000622200. J Biol Chem. 2000. PMID: 11050075 Free article.

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