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Delayed Mucosal Antiviral Responses Despite Robust Peripheral Inflammation in Fatal COVID-19.
Sidhu JK, Siggins MK, Liew F, Russell CD, Uruchurtu ASS, Davis C, Turtle L, Moore SC, Hardwick HE, Oosthuyzen W, Thomson EC, Semple MG, Baillie JK, Openshaw PJM, Thwaites RS; ISARIC4C investigators. Sidhu JK, et al. J Infect Dis. 2024 Jul 25;230(1):e17-e29. doi: 10.1093/infdis/jiad590. J Infect Dis. 2024. PMID: 39052740 Free PMC article.
Relative deficiency in interferon-γ-secreting CD4+ T cells is strongly associated with poorer COVID-19 vaccination responses in older adults.
Ho VWT, Boon LH, Cui J, Juequn Z, Shunmuganathan B, Gupta R, Tan NYJ, Qian X, Purushotorman K; SCOPE Cohort Study Group; Fong SW, Renia L, Ng LFP, Angeli V, Chen J, Kennedy BK, Ong CWM, Macary PA. Ho VWT, et al. Aging Cell. 2024 Apr;23(4):e14099. doi: 10.1111/acel.14099. Epub 2024 Feb 5. Aging Cell. 2024. PMID: 38317404 Free PMC article.
Evaluation of eight lateral flow tests for the detection of anti-SARS-CoV-2 antibodies in a vaccinated population.
Greenland-Bews C, Byrne RL, Owen SI, Watkins RL, Bengey D, Buist K, Clerkin K, Escadafal C, Finch LS, Gould S, Giorgi E, Hodgkinson A, Mashenko L, Powell D, Savage HR, Thompson CR, Turtle L, Wardale J, Wooding D, Edwards T, Atienzar AC, Adams ER. Greenland-Bews C, et al. BMC Infect Dis. 2023 Feb 23;23(1):110. doi: 10.1186/s12879-023-08033-1. BMC Infect Dis. 2023. PMID: 36823583 Free PMC article.
SARS-CoV-2 population dynamics in immunocompetent individuals in a closed transmission chain shows genomic diversity over the course of infection.
Goldswain H, Penrice-Randal R, Donovan-Banfield I, Duffy CW, Dong X, Randle N, Ryan Y, Rzeszutek AM, Pilgrim J, Keyser E, Weller SA, Hutley EJ, Hartley C, Prince T, Darby AC, Aye Maung N, Nwume H, Hiscox JA, Emmett SR. Goldswain H, et al. Genome Med. 2024 Jul 16;16(1):89. doi: 10.1186/s13073-024-01360-1. Genome Med. 2024. PMID: 39014481 Free PMC article.
Can self-testing be enhanced to hasten safe return of healthcare workers in pandemics? Random order, open label trial using two manufacturers' SARS-CoV-2 lateral flow devices concurrently and nested viral culture study.
Zhang X, Cheyne CP, Jones C, Humann M, Leeming G, Smith C, Hughes DM, Burnside G, Dodd S, Penrice-Randal R, Dong X, Semple MG, Neal T, Tunkel S, Fowler T, Turtle L, García-Fiñana M, Buchan IE. Zhang X, et al. BMC Infect Dis. 2024 Nov 11;24(1):1276. doi: 10.1186/s12879-024-10155-z. BMC Infect Dis. 2024. PMID: 39528957 Free PMC article. Clinical Trial.