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2010 3
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15 results

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Page 1
CLEC-2 activates Syk through dimerization.
Hughes CE, Pollitt AY, Mori J, Eble JA, Tomlinson MG, Hartwig JH, O'Callaghan CA, Fütterer K, Watson SP. Hughes CE, et al. Blood. 2010 Apr 8;115(14):2947-55. doi: 10.1182/blood-2009-08-237834. Epub 2010 Feb 12. Blood. 2010. PMID: 20154219 Free PMC article.
G6f-like is an ITAM-containing collagen receptor in thrombocytes.
Hughes CE, Radhakrishnan UP, Lordkipanidzé M, Egginton S, Dijkstra JM, Jagadeeswaran P, Watson SP. Hughes CE, et al. PLoS One. 2012;7(12):e52622. doi: 10.1371/journal.pone.0052622. Epub 2012 Dec 21. PLoS One. 2012. PMID: 23285115 Free PMC article.
Fibrin activates GPVI in human and mouse platelets.
Alshehri OM, Hughes CE, Montague S, Watson SK, Frampton J, Bender M, Watson SP. Alshehri OM, et al. Blood. 2015 Sep 24;126(13):1601-8. doi: 10.1182/blood-2015-04-641654. Epub 2015 Aug 17. Blood. 2015. PMID: 26282541 Free PMC article.
CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.
Finney BA, Schweighoffer E, Navarro-Núñez L, Bénézech C, Barone F, Hughes CE, Langan SA, Lowe KL, Pollitt AY, Mourao-Sa D, Sheardown S, Nash GB, Smithers N, Reis e Sousa C, Tybulewicz VL, Watson SP. Finney BA, et al. Blood. 2012 Feb 16;119(7):1747-56. doi: 10.1182/blood-2011-09-380709. Epub 2011 Dec 20. Blood. 2012. PMID: 22186994 Free PMC article.
CLEC-2 is not required for platelet aggregation at arteriolar shear.
Hughes CE, Navarro-Núñez L, Finney BA, Mourão-Sá D, Pollitt AY, Watson SP. Hughes CE, et al. J Thromb Haemost. 2010 Oct;8(10):2328-2332. doi: 10.1111/j.1538-7836.2010.04006.x. J Thromb Haemost. 2010. PMID: 20695981 Free PMC article. No abstract available.
Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets.
Hitchcock JR, Cook CN, Bobat S, Ross EA, Flores-Langarica A, Lowe KL, Khan M, Dominguez-Medina CC, Lax S, Carvalho-Gaspar M, Hubscher S, Rainger GE, Cobbold M, Buckley CD, Mitchell TJ, Mitchell A, Jones ND, Van Rooijen N, Kirchhofer D, Henderson IR, Adams DH, Watson SP, Cunningham AF. Hitchcock JR, et al. J Clin Invest. 2015 Dec;125(12):4429-46. doi: 10.1172/JCI79070. Epub 2015 Nov 16. J Clin Invest. 2015. PMID: 26571395 Free PMC article.
15 results