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Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin-2 Receptor: Structure-Activity Relationships and Optimization.
Zirimwabagabo JO, Jailani ABA, Avgoustou P, Tozer MJ, Gibson KR, Glossop PA, Mills JEJ, Porter RA, Blaney P, Wang N, Skerry TM, Richards GO, Harrity JPA. Zirimwabagabo JO, et al. J Med Chem. 2021 Mar 25;64(6):3299-3319. doi: 10.1021/acs.jmedchem.0c02191. Epub 2021 Mar 5. J Med Chem. 2021. PMID: 33666424 Free PMC article.