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Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes.
Harpelunde Poulsen K, Nielsen JE, Frederiksen H, Melau C, Juul Hare K, Langhoff Thuesen L, Perlman S, Lundvall L, Mitchell RT, Juul A, Rajpert-De Meyts E, Jørgensen A. Harpelunde Poulsen K, et al. Hum Reprod. 2019 Nov 1;34(11):2228-2243. doi: 10.1093/humrep/dez191. Hum Reprod. 2019. PMID: 31734698 Free PMC article.
Ibuprofen results in alterations of human fetal testis development.
Ben Maamar M, Lesné L, Hennig K, Desdoits-Lethimonier C, Kilcoyne KR, Coiffec I, Rolland AD, Chevrier C, Kristensen DM, Lavoué V, Antignac JP, Le Bizec B, Dejucq-Rainsford N, Mitchell RT, Mazaud-Guittot S, Jégou B. Ben Maamar M, et al. Sci Rep. 2017 Mar 10;7:44184. doi: 10.1038/srep44184. Sci Rep. 2017. PMID: 28281692 Free PMC article.
Effects of Exposure to Acetaminophen and Ibuprofen on Fetal Germ Cell Development in Both Sexes in Rodent and Human Using Multiple Experimental Systems.
Hurtado-Gonzalez P, Anderson RA, Macdonald J, van den Driesche S, Kilcoyne K, Jørgensen A, McKinnell C, Macpherson S, Sharpe RM, Mitchell RT. Hurtado-Gonzalez P, et al. Environ Health Perspect. 2018 Apr 16;126(4):047006. doi: 10.1289/EHP2307. Environ Health Perspect. 2018. PMID: 29665328 Free PMC article.
Intratubular germ cell neoplasia of the human testis: heterogeneous protein expression and relation to invasive potential.
Mitchell RT, Camacho-Moll M, Macdonald J, Anderson RA, Kelnar CJ, O'Donnell M, Sharpe RM, Smith LB, Grigor KM, Wallace WHB, Stoop H, Wolffenbuttel KP, Donat R, Saunders PT, Looijenga LH. Mitchell RT, et al. Mod Pathol. 2014 Sep;27(9):1255-1266. doi: 10.1038/modpathol.2013.246. Epub 2014 Jan 24. Mod Pathol. 2014. PMID: 24457464 Free PMC article.
11 results