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Page 1
Interferon-Gamma-Producing CD8+ Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor-Colitis.
Sasson SC, Slevin SM, Cheung VTF, Nassiri I, Olsson-Brown A, Fryer E, Ferreira RC, Trzupek D, Gupta T, Al-Hillawi L, Issaias ML, Easton A, Campo L, FitzPatrick MEB, Adams J, Chitnis M, Protheroe A, Tuthill M, Coupe N, Simmons A, Payne M, Middleton MR, Travis SPL; Oxford Inflammatory Bowel Disease Cohort Investigators; Fairfax BP, Klenerman P, Brain O. Sasson SC, et al. Gastroenterology. 2021 Oct;161(4):1229-1244.e9. doi: 10.1053/j.gastro.2021.06.025. Epub 2021 Jun 17. Gastroenterology. 2021. PMID: 34147519 Free PMC article.
Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cells.
Inaba A, Tuong ZK, Zhao TX, Stewart AP, Mathews R, Truman L, Sriranjan R, Kennet J, Saeb-Parsy K, Wicker L, Waldron-Lynch F, Cheriyan J, Todd JA, Mallat Z, Clatworthy MR. Inaba A, et al. Nat Commun. 2023 Apr 12;14(1):2071. doi: 10.1038/s41467-023-37424-w. Nat Commun. 2023. PMID: 37045832 Free PMC article.
Assessing the effect of closed-loop insulin delivery from onset of type 1 diabetes in youth on residual beta-cell function compared to standard insulin therapy (CLOuD study): a randomised parallel study protocol.
Boughton C, Allen JM, Tauschmann M, Hartnell S, Wilinska ME, Musolino G, Acerini CL, Dunger PD, Campbell F, Ghatak A, Randell T, Besser R, Trevelyan N, Elleri D, Northam E, Hood K, Scott E, Lawton J, Roze S, Sibayan J, Kollman C, Cohen N, Todd J, Hovorka R; CLOuD Consortium. Boughton C, et al. BMJ Open. 2020 Mar 12;10(3):e033500. doi: 10.1136/bmjopen-2019-033500. BMJ Open. 2020. PMID: 32169925 Free PMC article.
Therapeutically expanded human regulatory T-cells are super-suppressive due to HIF1A induced expression of CD73.
Jarvis LB, Rainbow DB, Coppard V, Howlett SK, Georgieva Z, Davies JL, Mullay HK, Hester J, Ashmore T, Van Den Bosch A, Grist JT, Coles AJ, Mousa HS, Pluchino S, Mahbubani KT, Griffin JL, Saeb-Parsy K, Issa F, Peruzzotti-Jametti L, Wicker LS, Jones JL. Jarvis LB, et al. Commun Biol. 2021 Oct 14;4(1):1186. doi: 10.1038/s42003-021-02721-x. Commun Biol. 2021. PMID: 34650224 Free PMC article.
Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration.
Carr ALJ, Inshaw JRJ, Flaxman CS, Leete P, Wyatt RC, Russell LA, Palmer M, Prasolov D, Worthington T, Hull B, Wicker LS, Dunger DB, Oram RA, Morgan NG, Todd JA, Richardson SJ, Besser REJ. Carr ALJ, et al. Diabetes. 2022 Jul 1;71(7):1591-1596. doi: 10.2337/db22-0097. Diabetes. 2022. PMID: 35499624 Free PMC article.