Recovery of natural killer cell cytotoxicity in a p.A91V perforin homozygous patient following severe haemophagocytic lymphohistiocytosis

Br J Haematol. 2020 Aug;190(3):458-461. doi: 10.1111/bjh.16660. Epub 2020 Apr 27.

Helena S Jang^{1

2}, Thijs W H Flinsenberg³, Paul Lacaze⁴, Kevin Y T Thia⁵, Tahereh Noori³, Suran L Fernando^{1

2

6}, Ian Kerridge⁷, Moeen Riaz⁴, John J McNeil⁴, Piers A Blombery^{8

9}, Joseph A Trapani^{5

8}, Ilia Voskoboinik^{3

8}

¹ Immunorheumatology Laboratory, New South Wales Health Pathology, Royal North Shore Hospital, Sydney, Australia.
² Department of Clinical Immunology and Allergy, Royal North Shore Hospital, Sydney, Australia.
³ Cancer Immunology Program, Killer Cell Biology Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
⁴ Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
⁵ Cancer Immunology Program, Cancer Cell Death Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
⁶ The University of Sydney, Sydney, Australia.
⁷ Department of Haematology, Royal North Shore Hospital, Sydney, Australia.
⁸ Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia.
⁹ Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

No abstract available

Keywords: A91V.

Publication types