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Loss of Lkb1 in CD11c+ myeloid cells protects mice from diet-induced obesity while enhancing glucose intolerance and IL-17/IFN-γ imbalance.
Sun Y, Wang B, Hu Q, Zhang H, Lai X, Wang T, Zhao C, Wang J, Zhang X, Niu Q, He B, Jiang E, Shi M, Feng X, Luo Y. Sun Y, et al. Cell Mol Life Sci. 2023 Feb 13;80(3):63. doi: 10.1007/s00018-023-04707-w. Cell Mol Life Sci. 2023. PMID: 36781473 Free PMC article.
Here, we demonstrated that liver kinase B1 (Lkb1), a key bioenergetic sensor, is involved in CD11c(+) cell-mediated immune responses in diet-induced obesity. ...
Here, we demonstrated that liver kinase B1 (Lkb1), a key bioenergetic sensor, is involved in CD11c(+) cell-mediated immune responses …