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Year Number of Results
2014 2
2015 23
2016 25
2017 30
2018 28
2019 20
2020 24
2021 41
2022 3
2024 0

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169 results

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Page 1
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.
Vlachogiannis G, Hedayat S, Vatsiou A, Jamin Y, Fernández-Mateos J, Khan K, Lampis A, Eason K, Huntingford I, Burke R, Rata M, Koh DM, Tunariu N, Collins D, Hulkki-Wilson S, Ragulan C, Spiteri I, Moorcraft SY, Chau I, Rao S, Watkins D, Fotiadis N, Bali M, Darvish-Damavandi M, Lote H, Eltahir Z, Smyth EC, Begum R, Clarke PA, Hahne JC, Dowsett M, de Bono J, Workman P, Sadanandam A, Fassan M, Sansom OJ, Eccles S, Starling N, Braconi C, Sottoriva A, Robinson SP, Cunningham D, Valeri N. Vlachogiannis G, et al. Science. 2018 Feb 23;359(6378):920-926. doi: 10.1126/science.aao2774. Science. 2018. PMID: 29472484 Free PMC article.
Advances in colon cancer research: in vitro and animal models.
Lannagan TR, Jackstadt R, Leedham SJ, Sansom OJ. Lannagan TR, et al. Curr Opin Genet Dev. 2021 Feb;66:50-56. doi: 10.1016/j.gde.2020.12.003. Epub 2021 Jan 7. Curr Opin Genet Dev. 2021. PMID: 33422950 Free PMC article. Review.
Genomic analyses identify molecular subtypes of pancreatic cancer.
Bailey P, Chang DK, Nones K, Johns AL, Patch AM, Gingras MC, Miller DK, Christ AN, Bruxner TJ, Quinn MC, Nourse C, Murtaugh LC, Harliwong I, Idrisoglu S, Manning S, Nourbakhsh E, Wani S, Fink L, Holmes O, Chin V, Anderson MJ, Kazakoff S, Leonard C, Newell F, Waddell N, Wood S, Xu Q, Wilson PJ, Cloonan N, Kassahn KS, Taylor D, Quek K, Robertson A, Pantano L, Mincarelli L, Sanchez LN, Evers L, Wu J, Pinese M, Cowley MJ, Jones MD, Colvin EK, Nagrial AM, Humphrey ES, Chantrill LA, Mawson A, Humphris J, Chou A, Pajic M, Scarlett CJ, Pinho AV, Giry-Laterriere M, Rooman I, Samra JS, Kench JG, Lovell JA, Merrett ND, Toon CW, Epari K, Nguyen NQ, Barbour A, Zeps N, Moran-Jones K, Jamieson NB, Graham JS, Duthie F, Oien K, Hair J, Grützmann R, Maitra A, Iacobuzio-Donahue CA, Wolfgang CL, Morgan RA, Lawlor RT, Corbo V, Bassi C, Rusev B, Capelli P, Salvia R, Tortora G, Mukhopadhyay D, Petersen GM; Australian Pancreatic Cancer Genome Initiative; Munzy DM, Fisher WE, Karim SA, Eshleman JR, Hruban RH, Pilarsky C, Morton JP, Sansom OJ, Scarpa A, Musgrove EA, Bailey UM, Hofmann O, Sutherland RL, Wheeler DA, Gill AJ, Gibbs RA, Pearson JV, Waddell N, Biankin AV, Grimmond SM. Bailey P, et al. Nature. 2016 Mar 3;531(7592):47-52. doi: 10.1038/nature16965. Epub 2016 Feb 24. Nature. 2016. PMID: 26909576
Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity.
Hutton C, Heider F, Blanco-Gomez A, Banyard A, Kononov A, Zhang X, Karim S, Paulus-Hock V, Watt D, Steele N, Kemp S, Hogg EKJ, Kelly J, Jackstadt RF, Lopes F, Menotti M, Chisholm L, Lamarca A, Valle J, Sansom OJ, Springer C, Malliri A, Marais R, Pasca di Magliano M, Zelenay S, Morton JP, Jørgensen C. Hutton C, et al. Cancer Cell. 2021 Sep 13;39(9):1227-1244.e20. doi: 10.1016/j.ccell.2021.06.017. Epub 2021 Jul 22. Cancer Cell. 2021. PMID: 34297917 Free PMC article.
Mannose impairs tumour growth and enhances chemotherapy.
Gonzalez PS, O'Prey J, Cardaci S, Barthet VJA, Sakamaki JI, Beaumatin F, Roseweir A, Gay DM, Mackay G, Malviya G, Kania E, Ritchie S, Baudot AD, Zunino B, Mrowinska A, Nixon C, Ennis D, Hoyle A, Millan D, McNeish IA, Sansom OJ, Edwards J, Ryan KM. Gonzalez PS, et al. Nature. 2018 Nov;563(7733):719-723. doi: 10.1038/s41586-018-0729-3. Epub 2018 Nov 21. Nature. 2018. PMID: 30464341 Free article.
Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Maddocks ODK, Athineos D, Cheung EC, Lee P, Zhang T, van den Broek NJF, Mackay GM, Labuschagne CF, Gay D, Kruiswijk F, Blagih J, Vincent DF, Campbell KJ, Ceteci F, Sansom OJ, Blyth K, Vousden KH. Maddocks ODK, et al. Nature. 2017 Apr 19;544(7650):372-376. doi: 10.1038/nature22056. Nature. 2017. PMID: 28425994 Free article.
Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition.
Sharbeen G, McCarroll JA, Akerman A, Kopecky C, Youkhana J, Kokkinos J, Holst J, Boyer C, Erkan M, Goldstein D, Timpson P, Cox TR, Pereira BA, Chitty JL, Fey SK, Najumudeen AK, Campbell AD, Sansom OJ, Ignacio RMC, Naim S, Liu J, Russia N, Lee J, Chou A, Johns A, Gill AJ, Gonzales-Aloy E, Gebski V, Guan YF, Pajic M, Turner N, Apte MV, Davis TP, Morton JP, Haghighi KS, Kasparian J, McLean BJ, Setargew YF, Phillips PA; Australian Pancreatic Cancer Genome Initiative. Sharbeen G, et al. Cancer Res. 2021 Jul 1;81(13):3461-3479. doi: 10.1158/0008-5472.CAN-20-2496. Epub 2021 May 12. Cancer Res. 2021. PMID: 33980655
Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.
Jackstadt R, van Hooff SR, Leach JD, Cortes-Lavaud X, Lohuis JO, Ridgway RA, Wouters VM, Roper J, Kendall TJ, Roxburgh CS, Horgan PG, Nixon C, Nourse C, Gunzer M, Clark W, Hedley A, Yilmaz OH, Rashid M, Bailey P, Biankin AV, Campbell AD, Adams DJ, Barry ST, Steele CW, Medema JP, Sansom OJ. Jackstadt R, et al. Cancer Cell. 2019 Sep 16;36(3):319-336.e7. doi: 10.1016/j.ccell.2019.08.003. Cancer Cell. 2019. PMID: 31526760 Free PMC article.
Mouse models of intestinal cancer.
Jackstadt R, Sansom OJ. Jackstadt R, et al. J Pathol. 2016 Jan;238(2):141-51. doi: 10.1002/path.4645. Epub 2015 Oct 29. J Pathol. 2016. PMID: 26414675 Free PMC article. Review.
169 results