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2017 1
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2020 5
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14 results

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Page 1
Pan-cancer analysis of whole genomes.
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium. ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium. Nature. 2020 Feb;578(7793):82-93. doi: 10.1038/s41586-020-1969-6. Epub 2020 Feb 5. Nature. 2020. PMID: 32025007 Free PMC article.
Somatic mutant clones colonize the human esophagus with age.
Martincorena I, Fowler JC, Wabik A, Lawson ARJ, Abascal F, Hall MWJ, Cagan A, Murai K, Mahbubani K, Stratton MR, Fitzgerald RC, Handford PA, Campbell PJ, Saeb-Parsy K, Jones PH. Martincorena I, et al. Science. 2018 Nov 23;362(6417):911-917. doi: 10.1126/science.aau3879. Epub 2018 Oct 18. Science. 2018. PMID: 30337457 Free PMC article.
Molecular phenotyping reveals the identity of Barrett's esophagus and its malignant transition.
Nowicki-Osuch K, Zhuang L, Jammula S, Bleaney CW, Mahbubani KT, Devonshire G, Katz-Summercorn A, Eling N, Wilbrey-Clark A, Madissoon E, Gamble J, Di Pietro M, O'Donovan M, Meyer KB, Saeb-Parsy K, Sharrocks AD, Teichmann SA, Marioni JC, Fitzgerald RC. Nowicki-Osuch K, et al. Science. 2021 Aug 13;373(6556):760-767. doi: 10.1126/science.abd1449. Science. 2021. PMID: 34385390
Pathologic Lymph Node Regression After Neoadjuvant Chemotherapy Predicts Recurrence and Survival in Esophageal Adenocarcinoma: A Multicenter Study in the United Kingdom.
Moore JL, Green M, Santaolalla A, Deere H, Evans RPT, Elshafie M, Lavery A, McManus DT, McGuigan A, Douglas R, Horne J, Walker R, Mir H, Terlizzo M, Kamarajah SK, Van Hemelrijck M, Maisey N, Sita-Lumsden A, Ngan S, Kelly M, Baker CR, Kumar S, Lagergren J, Allum WH, Gossage JA, Griffiths EA, Grabsch HI, Turkington RC, Underwood TJ, Smyth EC, Fitzgerald RC, Cunningham D, Davies AR; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) study group, The Guy's and St Thomas' Oesophago-gastric Research Group, and The PROGRESS study group. Moore JL, et al. J Clin Oncol. 2023 Oct 1;41(28):4522-4534. doi: 10.1200/JCO.23.00139. Epub 2023 Jul 27. J Clin Oncol. 2023. PMID: 37499209
Identification of Subtypes of Barrett's Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data.
Jammula S, Katz-Summercorn AC, Li X, Linossi C, Smyth E, Killcoyne S, Biasci D, Subash VV, Abbas S, Blasko A, Devonshire G, Grantham A, Wronowski F, O'Donovan M, Grehan N, Eldridge MD, Tavaré S; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) consortium; Fitzgerald RC. Jammula S, et al. Gastroenterology. 2020 May;158(6):1682-1697.e1. doi: 10.1053/j.gastro.2020.01.044. Epub 2020 Feb 4. Gastroenterology. 2020. PMID: 32032585 Free PMC article.
Longitudinal tracking of 97 esophageal adenocarcinomas using liquid biopsy sampling.
Ococks E, Frankell AM, Masque Soler N, Grehan N, Northrop A, Coles H, Redmond AM, Devonshire G, Weaver JMJ, Hughes C, Lehovsky K, Blasko A, Nutzinger B; OCCAMS Consortium; Fitzgerald RC, Smyth E. Ococks E, et al. Ann Oncol. 2021 Apr;32(4):522-532. doi: 10.1016/j.annonc.2020.12.010. Epub 2021 Jan 7. Ann Oncol. 2021. PMID: 33359547 Free article.
Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics.
Li X, Francies HE, Secrier M, Perner J, Miremadi A, Galeano-Dalmau N, Barendt WJ, Letchford L, Leyden GM, Goffin EK, Barthorpe A, Lightfoot H, Chen E, Gilbert J, Noorani A, Devonshire G, Bower L, Grantham A, MacRae S, Grehan N, Wedge DC, Fitzgerald RC, Garnett MJ. Li X, et al. Nat Commun. 2018 Jul 30;9(1):2983. doi: 10.1038/s41467-018-05190-9. Nat Commun. 2018. PMID: 30061675 Free PMC article.
Machine learning to predict early recurrence after oesophageal cancer surgery.
Rahman SA, Walker RC, Lloyd MA, Grace BL, van Boxel GI, Kingma BF, Ruurda JP, van Hillegersberg R, Harris S, Parsons S, Mercer S, Griffiths EA, O'Neill JR, Turkington R, Fitzgerald RC, Underwood TJ; OCCAMS Consortium. Rahman SA, et al. Br J Surg. 2020 Jul;107(8):1042-1052. doi: 10.1002/bjs.11461. Epub 2020 Jan 30. Br J Surg. 2020. PMID: 31997313 Free PMC article.
Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma.
Noorani A, Li X, Goddard M, Crawte J, Alexandrov LB, Secrier M, Eldridge MD, Bower L, Weaver J, Lao-Sirieix P, Martincorena I, Debiram-Beecham I, Grehan N, MacRae S, Malhotra S, Miremadi A, Thomas T, Galbraith S, Petersen L, Preston SD, Gilligan D, Hindmarsh A, Hardwick RH, Stratton MR, Wedge DC, Fitzgerald RC. Noorani A, et al. Nat Genet. 2020 Jan;52(1):74-83. doi: 10.1038/s41588-019-0551-3. Epub 2020 Jan 6. Nat Genet. 2020. PMID: 31907488 Free PMC article.
14 results