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Standardised animal models of host microbial mutualism.
Macpherson AJ, McCoy KD. Macpherson AJ, et al. Mucosal Immunol. 2015 May;8(3):476-86. doi: 10.1038/mi.2014.113. Epub 2014 Dec 10. Mucosal Immunol. 2015. PMID: 25492472 Free PMC article. Review.
The outer mucus layer hosts a distinct intestinal microbial niche.
Li H, Limenitakis JP, Fuhrer T, Geuking MB, Lawson MA, Wyss M, Brugiroux S, Keller I, Macpherson JA, Rupp S, Stolp B, Stein JV, Stecher B, Sauer U, McCoy KD, Macpherson AJ. Li H, et al. Nat Commun. 2015 Sep 22;6:8292. doi: 10.1038/ncomms9292. Nat Commun. 2015. PMID: 26392213 Free PMC article.
T Follicular Helper Cells Promote a Beneficial Gut Ecosystem for Host Metabolic Homeostasis by Sensing Microbiota-Derived Extracellular ATP.
Perruzza L, Gargari G, Proietti M, Fosso B, D'Erchia AM, Faliti CE, Rezzonico-Jost T, Scribano D, Mauri L, Colombo D, Pellegrini G, Moregola A, Mooser C, Pesole G, Nicoletti M, Norata GD, Geuking MB, McCoy KD, Guglielmetti S, Grassi F. Perruzza L, et al. Cell Rep. 2017 Mar 14;18(11):2566-2575. doi: 10.1016/j.celrep.2017.02.061. Cell Rep. 2017. PMID: 28297661 Free PMC article.
Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse Model.
Studer N, Desharnais L, Beutler M, Brugiroux S, Terrazos MA, Menin L, Schürch CM, McCoy KD, Kuehne SA, Minton NP, Stecher B, Bernier-Latmani R, Hapfelmeier S. Studer N, et al. Front Cell Infect Microbiol. 2016 Dec 20;6:191. doi: 10.3389/fcimb.2016.00191. eCollection 2016. Front Cell Infect Microbiol. 2016. PMID: 28066726 Free PMC article.