6950/CRUK_/Cancer Research UK/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2008	1
2009	2
2010	2
2011	3
2012	6
2013	6
2014	3
2015	2
2016	1
2024	0

1

Bivalent enzyme inhibitors discovered using dynamic covalent chemistry.

Clipson AJ, Bhat VT, McNae I, Caniard AM, Campopiano DJ, Greaney MF. Clipson AJ, et al. Chemistry. 2012 Aug 20;18(34):10562-70. doi: 10.1002/chem.201201507. Epub 2012 Jul 10. Chemistry. 2012. PMID: 22782854 Free article.

2

Mechanism-specific signatures for small-molecule p53 activators.

van Leeuwen IM, Higgins M, Campbell J, Brown CJ, McCarthy AR, Pirrie L, Westwood NJ, Laín S. van Leeuwen IM, et al. Cell Cycle. 2011 May 15;10(10):1590-8. doi: 10.4161/cc.10.10.15519. Epub 2011 May 15. Cell Cycle. 2011. PMID: 21490429

3

Synthesis and biological characterisation of sirtuin inhibitors based on the tenovins.

McCarthy AR, Pirrie L, Hollick JJ, Ronseaux S, Campbell J, Higgins M, Staples OD, Tran F, Slawin AM, Lain S, Westwood NJ. McCarthy AR, et al. Bioorg Med Chem. 2012 Mar 1;20(5):1779-93. doi: 10.1016/j.bmc.2012.01.001. Epub 2012 Jan 12. Bioorg Med Chem. 2012. PMID: 22304848

4

ALDH2 mediates 5-nitrofuran activity in multiple species.

Zhou L, Ishizaki H, Spitzer M, Taylor KL, Temperley ND, Johnson SL, Brear P, Gautier P, Zeng Z, Mitchell A, Narayan V, McNeil EM, Melton DW, Smith TK, Tyers M, Westwood NJ, Patton EE. Zhou L, et al. Chem Biol. 2012 Jul 27;19(7):883-92. doi: 10.1016/j.chembiol.2012.05.017. Chem Biol. 2012. PMID: 22840776 Free PMC article.

5

An asymmetric pericyclic cascade approach to 3-alkyl-3-aryloxindoles: generality, applications and mechanistic investigations.

Richmond E, Ling KB, Duguet N, Manton LB, Çelebi-Ölçüm N, Lam YH, Alsancak S, Slawin AM, Houk KN, Smith AD. Richmond E, et al. Org Biomol Chem. 2015 Feb 14;13(6):1807-17. doi: 10.1039/c4ob02526a. Org Biomol Chem. 2015. PMID: 25501712 Free article.

6

The benzyne aza-Claisen reaction.

Cant AA, Bertrand GH, Henderson JL, Roberts L, Greaney MF. Cant AA, et al. Angew Chem Int Ed Engl. 2009;48(28):5199-202. doi: 10.1002/anie.200901410. Angew Chem Int Ed Engl. 2009. PMID: 19526475

7

Inhibition of protein synthesis and JNK activation are not required for cell death induced by anisomycin and anisomycin analogues.

Monaghan D, O'Connell E, Cruickshank FL, O'Sullivan B, Giles FJ, Hulme AN, Fearnhead HO. Monaghan D, et al. Biochem Biophys Res Commun. 2014 Jan 10;443(2):761-7. doi: 10.1016/j.bbrc.2013.12.041. Epub 2013 Dec 12. Biochem Biophys Res Commun. 2014. PMID: 24333448 Free article.

8

Self-Assembly of Disorazole C1 through a One-Pot Alkyne Metathesis Homodimerization Strategy.

Ralston KJ, Ramstadius HC, Brewster RC, Niblock HS, Hulme AN. Ralston KJ, et al. Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7086-90. doi: 10.1002/anie.201501922. Epub 2015 Apr 29. Angew Chem Int Ed Engl. 2015. PMID: 25926364 Free PMC article.

9

Synthesis and biological evaluation of nitric oxide-donating analogues of sulindac for prostate cancer treatment.

Nortcliffe A, Ekstrom AG, Black JR, Ross JA, Habib FK, Botting NP, O'Hagan D. Nortcliffe A, et al. Bioorg Med Chem. 2014 Jan 15;22(2):756-61. doi: 10.1016/j.bmc.2013.12.014. Epub 2013 Dec 12. Bioorg Med Chem. 2014. PMID: 24387865

10

Novel cambinol analogs as sirtuin inhibitors: synthesis, biological evaluation, and rationalization of activity.

Medda F, Russell RJ, Higgins M, McCarthy AR, Campbell J, Slawin AM, Lane DP, Lain S, Westwood NJ. Medda F, et al. J Med Chem. 2009 May 14;52(9):2673-82. doi: 10.1021/jm8014298. J Med Chem. 2009. PMID: 19419202 Free PMC article.

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