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Lipid Nanoparticle Encapsulation Empowers Poly(I:C) to Activate Cytoplasmic RLRs and Thereby Increases Its Adjuvanticity.
Lamoot A, Jangra S, Laghlali G, Warang P, Singh G, Chang LA, Park SC, Singh G, De Swarte K, Zhong Z, Louage B, De Lombaerde E, Ye T, Chen Y, Cuadrado-Castano S, Lienenklaus S, Sanders NN, Lambrecht BN, García-Sastre A, Schotsaert M, De Geest BG. Lamoot A, et al. Small. 2024 Mar;20(10):e2306892. doi: 10.1002/smll.202306892. Epub 2023 Oct 22. Small. 2024. PMID: 37867244
Host immune responses associated with SARS-CoV-2 Omicron infection result in protection or pathology during reinfection depending on mouse genetic background.
Singh G, Warang P, García-Bernalt Diego J, Chang L, Bykov Y, Singh S, Pache L, Cuadrado-Castano S, Webb B, Garcia-Sastre A, Schotsaert M. Singh G, et al. Res Sq [Preprint]. 2023 Nov 29:rs.3.rs-3637405. doi: 10.21203/rs.3.rs-3637405/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Nov 23;15(1):10178. doi: 10.1038/s41467-024-54334-7 PMID: 38077015 Free PMC article. Updated. Preprint.
A multicomponent intranasal adjuvant drives durable humoral, cellular, and mucosal immune responses to SARS-CoV-2 in young and aged mice.
Jangra S, Landers JJ, Laghlali G, Rathnasinghe R, O'Konek JJ, Janczak KW, García-Sastre A, Baker JR Jr, Schotsaert M, Wong PT. Jangra S, et al. Res Sq [Preprint]. 2023 Jan 20:rs.3.rs-2457013. doi: 10.21203/rs.3.rs-2457013/v1. Res Sq. 2023. Update in: NPJ Vaccines. 2023 Jun 29;8(1):96. doi: 10.1038/s41541-023-00691-1 PMID: 36711479 Free PMC article. Updated. Preprint.
Outcome of SARS-CoV-2 reinfection depends on genetic background in female mice.
Singh G, García-Bernalt Diego J, Warang P, Park SC, Chang LA, Noureddine M, Laghlali G, Bykov Y, Prellberg M, Yan V, Singh S, Pache L, Cuadrado-Castano S, Webb B, García-Sastre A, Schotsaert M. Singh G, et al. Nat Commun. 2024 Nov 23;15(1):10178. doi: 10.1038/s41467-024-54334-7. Nat Commun. 2024. PMID: 39580470 Free PMC article.