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Spaceflight induces changes in gene expression profiles linked to insulin and estrogen.
Mathyk BA, Tabetah M, Karim R, Zaksas V, Kim J, Anu RI, Muratani M, Tasoula A, Singh RS, Chen YK, Overbey E, Park J, Cope H, Fazelinia H, Povero D, Borg J, Klotz RV, Yu M, Young SL, Mason CE, Szewczyk N, St Clair RM, Karouia F, Beheshti A. Mathyk BA, et al. Commun Biol. 2024 Jun 11;7(1):692. doi: 10.1038/s42003-023-05213-2. Commun Biol. 2024. PMID: 38862620 Free PMC article.
Space radiation damage rescued by inhibition of key spaceflight associated miRNAs.
McDonald JT, Kim J, Farmerie L, Johnson ML, Trovao NS, Arif S, Siew K, Tsoy S, Bram Y, Park J, Overbey E, Ryon K, Haltom J, Singh U, Enguita FJ, Zaksas V, Guarnieri JW, Topper M, Wallace DC, Meydan C, Baylin S, Meller R, Muratani M, Porterfield DM, Kaufman B, Mori MA, Walsh SB, Sigaudo-Roussel D, Mebarek S, Bottini M, Marquette CA, Wurtele ES, Schwartz RE, Galeano D, Mason CE, Grabham P, Beheshti A. McDonald JT, et al. Nat Commun. 2024 Jun 11;15(1):4825. doi: 10.1038/s41467-024-48920-y. Nat Commun. 2024. PMID: 38862542 Free PMC article.
Ethical considerations for the age of non-governmental space exploration.
Seylani A, Galsinh AS, Tasoula A, I AR, Camera A, Calleja-Agius J, Borg J, Goel C, Kim J, Clark KB, Das S, Arif S, Boerrigter M, Coffey C, Szewczyk N, Mason CE, Manoli M, Karouia F, Schwertz H, Beheshti A, Tulodziecki D. Seylani A, et al. Nat Commun. 2024 Jun 11;15(1):4774. doi: 10.1038/s41467-023-44357-x. Nat Commun. 2024. PMID: 38862473 Free PMC article. Review.
Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology.
Cope H, Elsborg J, Demharter S, McDonald JT, Wernecke C, Parthasarathy H, Unadkat H, Chatrathi M, Claudio J, Reinsch S, Avci P, Zwart SR, Smith SM, Heer M, Muratani M, Meydan C, Overbey E, Kim J, Chin CR, Park J, Schisler JC, Mason CE, Szewczyk NJ, Willis CRG, Salam A, Beheshti A. Cope H, et al. Commun Med (Lond). 2024 Jun 11;4(1):106. doi: 10.1038/s43856-024-00532-9. Commun Med (Lond). 2024. PMID: 38862781 Free PMC article.