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The cysteine-rich region of respiratory syncytial virus attachment protein inhibits innate immunity elicited by the virus and endotoxin.
Polack FP, Irusta PM, Hoffman SJ, Schiatti MP, Melendi GA, Delgado MF, Laham FR, Thumar B, Hendry RM, Melero JA, Karron RA, Collins PL, Kleeberger SR. Polack FP, et al. Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8996-9001. doi: 10.1073/pnas.0409478102. Epub 2005 Jun 14. Proc Natl Acad Sci U S A. 2005. PMID: 15956195 Free PMC article.
C5 modulates airway hyperreactivity and pulmonary eosinophilia during enhanced respiratory syncytial virus disease by decreasing C3a receptor expression.
Melendi GA, Hoffman SJ, Karron RA, Irusta PM, Laham FR, Humbles A, Schofield B, Pan CH, Rabold R, Thumar B, Thumar A, Gerard NP, Mitzner W, Barnum SR, Gerard C, Kleeberger SR, Polack FP. Melendi GA, et al. J Virol. 2007 Jan;81(2):991-9. doi: 10.1128/JVI.01783-06. Epub 2006 Nov 1. J Virol. 2007. PMID: 17079327 Free PMC article.
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