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Radiogenomics in the Era of Advanced Radiotherapy.
Brothwell MRS, West CM, Dunning AM, Burnet NG, Barnett GC. Brothwell MRS, et al. Clin Oncol (R Coll Radiol). 2019 May;31(5):319-325. doi: 10.1016/j.clon.2019.02.006. Epub 2019 Mar 23. Clin Oncol (R Coll Radiol). 2019. PMID: 30914148 Review.
Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity.
Ahmed M, Dorling L, Kerns S, Fachal L, Elliott R, Partliament M, Rosenstein BS, Vega A, Gómez-Caamaño A, Barnett G, Dearnaley DP, Hall E, Sydes M, Burnet N, Pharoah PD, Eeles R, West CM. Ahmed M, et al. Br J Cancer. 2016 May 10;114(10):1165-74. doi: 10.1038/bjc.2016.94. Epub 2016 Apr 12. Br J Cancer. 2016. PMID: 27070714 Free PMC article.
A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.
Barnett GC, Thompson D, Fachal L, Kerns S, Talbot C, Elliott RM, Dorling L, Coles CE, Dearnaley DP, Rosenstein BS, Vega A, Symonds P, Yarnold J, Baynes C, Michailidou K, Dennis J, Tyrer JP, Wilkinson JS, Gómez-Caamaño A, Tanteles GA, Platte R, Mayes R, Conroy D, Maranian M, Luccarini C, Gulliford SL, Sydes MR, Hall E, Haviland J, Misra V, Titley J, Bentzen SM, Pharoah PD, Burnet NG, Dunning AM, West CM. Barnett GC, et al. Radiother Oncol. 2014 May;111(2):178-85. doi: 10.1016/j.radonc.2014.02.012. Epub 2014 Apr 28. Radiother Oncol. 2014. PMID: 24785509