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Year Number of Results
2006 1
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2010 9
2011 6
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2024 0

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26 results

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Page 1
Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors.
Sequist LV, Waltman BA, Dias-Santagata D, Digumarthy S, Turke AB, Fidias P, Bergethon K, Shaw AT, Gettinger S, Cosper AK, Akhavanfard S, Heist RS, Temel J, Christensen JG, Wain JC, Lynch TJ, Vernovsky K, Mark EJ, Lanuti M, Iafrate AJ, Mino-Kenudson M, Engelman JA. Sequist LV, et al. Sci Transl Med. 2011 Mar 23;3(75):75ra26. doi: 10.1126/scitranslmed.3002003. Sci Transl Med. 2011. PMID: 21430269 Free PMC article.
EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib.
Corcoran RB, Ebi H, Turke AB, Coffee EM, Nishino M, Cogdill AP, Brown RD, Della Pelle P, Dias-Santagata D, Hung KE, Flaherty KT, Piris A, Wargo JA, Settleman J, Mino-Kenudson M, Engelman JA. Corcoran RB, et al. Cancer Discov. 2012 Mar;2(3):227-35. doi: 10.1158/2159-8290.CD-11-0341. Epub 2012 Jan 16. Cancer Discov. 2012. PMID: 22448344 Free PMC article.
Differences underlying EGFR and HER2 oncogene addiction.
Faber AC, Wong KK, Engelman JA. Faber AC, et al. Cell Cycle. 2010 Mar 1;9(5):851-2. doi: 10.4161/cc.9.5.11096. Epub 2010 Mar 30. Cell Cycle. 2010. PMID: 20160489 Free PMC article. No abstract available.
The PI3K pathway as drug target in human cancer.
Courtney KD, Corcoran RB, Engelman JA. Courtney KD, et al. J Clin Oncol. 2010 Feb 20;28(6):1075-83. doi: 10.1200/JCO.2009.25.3641. Epub 2010 Jan 19. J Clin Oncol. 2010. PMID: 20085938 Free PMC article. Review.
Targeting the PI3K signaling pathway in cancer.
Wong KK, Engelman JA, Cantley LC. Wong KK, et al. Curr Opin Genet Dev. 2010 Feb;20(1):87-90. doi: 10.1016/j.gde.2009.11.002. Epub 2009 Dec 16. Curr Opin Genet Dev. 2010. PMID: 20006486 Free PMC article. Review.
Modeling oncogene addiction using RNA interference.
Rothenberg SM, Engelman JA, Le S, Riese DJ 2nd, Haber DA, Settleman J. Rothenberg SM, et al. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12480-4. doi: 10.1073/pnas.0803217105. Epub 2008 Aug 18. Proc Natl Acad Sci U S A. 2008. PMID: 18711136 Free PMC article.
Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors.
Carretero J, Shimamura T, Rikova K, Jackson AL, Wilkerson MD, Borgman CL, Buttarazzi MS, Sanofsky BA, McNamara KL, Brandstetter KA, Walton ZE, Gu TL, Silva JC, Crosby K, Shapiro GI, Maira SM, Ji H, Castrillon DH, Kim CF, García-Echeverría C, Bardeesy N, Sharpless NE, Hayes ND, Kim WY, Engelman JA, Wong KK. Carretero J, et al. Cancer Cell. 2010 Jun 15;17(6):547-59. doi: 10.1016/j.ccr.2010.04.026. Cancer Cell. 2010. PMID: 20541700 Free PMC article.
Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.
Turke AB, Zejnullahu K, Wu YL, Song Y, Dias-Santagata D, Lifshits E, Toschi L, Rogers A, Mok T, Sequist L, Lindeman NI, Murphy C, Akhavanfard S, Yeap BY, Xiao Y, Capelletti M, Iafrate AJ, Lee C, Christensen JG, Engelman JA, Jänne PA. Turke AB, et al. Cancer Cell. 2010 Jan 19;17(1):77-88. doi: 10.1016/j.ccr.2009.11.022. Cancer Cell. 2010. PMID: 20129249 Free PMC article.
26 results