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Cell cycle arrest by Kaposi's sarcoma-associated herpesvirus replication-associated protein is mediated at both the transcriptional and posttranslational levels by binding to CCAAT/enhancer-binding protein alpha and p21(CIP-1).
Wu FY, Wang SE, Tang QQ, Fujimuro M, Chiou CJ, Zheng Q, Chen H, Hayward SD, Lane MD, Hayward GS. Wu FY, et al. J Virol. 2003 Aug;77(16):8893-914. doi: 10.1128/jvi.77.16.8893-8914.2003. J Virol. 2003. PMID: 12885907 Free PMC article.
Role of CCAAT/enhancer-binding protein alpha (C/EBPalpha) in activation of the Kaposi's sarcoma-associated herpesvirus (KSHV) lytic-cycle replication-associated protein (RAP) promoter in cooperation with the KSHV replication and transcription activator (RTA) and RAP.
Wang SE, Wu FY, Fujimuro M, Zong J, Hayward SD, Hayward GS. Wang SE, et al. J Virol. 2003 Jan;77(1):600-23. doi: 10.1128/jvi.77.1.600-623.2003. J Virol. 2003. PMID: 12477864 Free PMC article.
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