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Page 1
Altered Gut Microbiome Composition and Function Are Associated With Gut Barrier Dysfunction in Healthy Relatives of Patients With Crohn's Disease.
Leibovitzh H, Lee SH, Xue M, Raygoza Garay JA, Hernandez-Rocha C, Madsen KL, Meddings JB, Guttman DS, Espin-Garcia O, Smith MI, Goethel A, Griffiths AM, Moayyedi P, Steinhart AH, Panaccione R, Huynh HQ, Jacobson K, Aumais G, Mack DR, Abreu MT, Bernstein CN, Marshall JK, Turner D, Xu W; CCC GEM Project Research Consortium; Turpin W, Croitoru K. Leibovitzh H, et al. Gastroenterology. 2022 Nov;163(5):1364-1376.e10. doi: 10.1053/j.gastro.2022.07.004. Epub 2022 Jul 16. Gastroenterology. 2022. PMID: 35850197
Gut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.
Raygoza Garay JA, Turpin W, Lee SH, Smith MI, Goethel A, Griffiths AM, Moayyedi P, Espin-Garcia O, Abreu M, Aumais GL, Bernstein CN, Biron IA, Cino M, Deslandres C, Dotan I, El-Matary W, Feagan B, Guttman DS, Huynh H, Dieleman LA, Hyams JS, Jacobson K, Mack D, Marshall JK, Otley A, Panaccione R, Ropeleski M, Silverberg MS, Steinhart AH, Turner D, Yerushalmi B, Paterson AD, Xu W; CCC GEM Project Research Consortium; Croitoru K. Raygoza Garay JA, et al. Gastroenterology. 2023 Sep;165(3):670-681. doi: 10.1053/j.gastro.2023.05.032. Epub 2023 May 30. Gastroenterology. 2023. PMID: 37263307
Determinants of IBD Heritability: Genes, Bugs, and More.
Turpin W, Goethel A, Bedrani L, Croitoru Mdcm K. Turpin W, et al. Inflamm Bowel Dis. 2018 May 18;24(6):1133-1148. doi: 10.1093/ibd/izy085. Inflamm Bowel Dis. 2018. PMID: 29701818 Free PMC article. Review.
Increased Intestinal Permeability Is Associated With Later Development of Crohn's Disease.
Turpin W, Lee SH, Raygoza Garay JA, Madsen KL, Meddings JB, Bedrani L, Power N, Espin-Garcia O, Xu W, Smith MI, Griffiths AM, Moayyedi P, Turner D, Seidman EG, Steinhart AH, Marshall JK, Jacobson K, Mack D, Huynh H, Bernstein CN, Paterson AD; Crohn’s and Colitis Canada Genetic Environmental Microbial Project Research Consortium; CCC GEM Project recruitment site directors include Maria Abreu; Croitoru K. Turpin W, et al. Gastroenterology. 2020 Dec;159(6):2092-2100.e5. doi: 10.1053/j.gastro.2020.08.005. Epub 2020 Aug 10. Gastroenterology. 2020. PMID: 32791132
Association of host genome with intestinal microbial composition in a large healthy cohort.
Turpin W, Espin-Garcia O, Xu W, Silverberg MS, Kevans D, Smith MI, Guttman DS, Griffiths A, Panaccione R, Otley A, Xu L, Shestopaloff K, Moreno-Hagelsieb G; GEM Project Research Consortium; Paterson AD, Croitoru K. Turpin W, et al. Nat Genet. 2016 Nov;48(11):1413-1417. doi: 10.1038/ng.3693. Epub 2016 Oct 3. Nat Genet. 2016. PMID: 27694960
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.
Wang J, Kurilshikov A, Radjabzadeh D, Turpin W, Croitoru K, Bonder MJ, Jackson MA, Medina-Gomez C, Frost F, Homuth G, Rühlemann M, Hughes D, Kim HN; MiBioGen Consortium Initiative; Spector TD, Bell JT, Steves CJ, Timpson N, Franke A, Wijmenga C, Meyer K, Kacprowski T, Franke L, Paterson AD, Raes J, Kraaij R, Zhernakova A. Wang J, et al. Microbiome. 2018 Jun 8;6(1):101. doi: 10.1186/s40168-018-0479-3. Microbiome. 2018. PMID: 29880062 Free PMC article.
FUT2 genotype and secretory status are not associated with fecal microbial composition and inferred function in healthy subjects.
Turpin W, Bedrani L, Espin-Garcia O, Xu W, Silverberg MS, Smith MI, Guttman DS, Griffiths A, Moayyedi P, Panaccione R, Huynh H, Steinhart H, Aumais G, Shestopaloff K, Dieleman LA, Turner D, Paterson AD, Croitoru K. Turpin W, et al. Gut Microbes. 2018 Jul 4;9(4):357-368. doi: 10.1080/19490976.2018.1445956. Epub 2018 Apr 27. Gut Microbes. 2018. PMID: 29533703 Free PMC article.
Associations of NOD2 polymorphisms with Erysipelotrichaceae in stool of in healthy first degree relatives of Crohn's disease subjects.
Turpin W, Bedrani L, Espin-Garcia O, Xu W, Silverberg MS, Smith MI, Garay JAR, Lee SH, Guttman DS, Griffiths A, Moayyedi P, Panaccione R, Huynh H, Steinhart HA, Aumais G, Dieleman LA, Turner D; CCC IBD GEM Project research team; Paterson AD, Croitoru K. Turpin W, et al. BMC Med Genet. 2020 Oct 15;21(1):204. doi: 10.1186/s12881-020-01115-w. BMC Med Genet. 2020. PMID: 33059653 Free PMC article.
Analysis of Genetic Association of Intestinal Permeability in Healthy First-degree Relatives of Patients with Crohn's Disease.
Turpin W, Espin-Garcia O, Bedrani L, Madsen K, Meddings JB, Raygoza Garay JA, Silverberg MS, Smith MI, Griffiths AM, Moayyedi P, Marshall JK, Mack D, Seidman EG, Ropeleski M, Feagan BG, Jacobson K, Turner D, Walters T, Paterson AD; CCC GEM Project Research Consortium; Xu W, Croitoru K. Turpin W, et al. Inflamm Bowel Dis. 2019 Oct 18;25(11):1796-1804. doi: 10.1093/ibd/izz116. Inflamm Bowel Dis. 2019. PMID: 31251335