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Oxytocin is an anabolic bone hormone.
Tamma R, Colaianni G, Zhu LL, DiBenedetto A, Greco G, Montemurro G, Patano N, Strippoli M, Vergari R, Mancini L, Colucci S, Grano M, Faccio R, Liu X, Li J, Usmani S, Bachar M, Bab I, Nishimori K, Young LJ, Buettner C, Iqbal J, Sun L, Zaidi M, Zallone A. Tamma R, et al. Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7149-54. doi: 10.1073/pnas.0901890106. Epub 2009 Apr 15. Proc Natl Acad Sci U S A. 2009. PMID: 19369205 Free PMC article.
Physiological loading of joints prevents cartilage degradation through CITED2.
Leong DJ, Li YH, Gu XI, Sun L, Zhou Z, Nasser P, Laudier DM, Iqbal J, Majeska RJ, Schaffler MB, Goldring MB, Cardoso L, Zaidi M, Sun HB. Leong DJ, et al. FASEB J. 2011 Jan;25(1):182-91. doi: 10.1096/fj.10-164277. Epub 2010 Sep 8. FASEB J. 2011. PMID: 20826544 Free PMC article.
Regulated production of the pituitary hormone oxytocin from murine and human osteoblasts.
Colaianni G, Di Benedetto A, Zhu LL, Tamma R, Li J, Greco G, Peng Y, Dell'Endice S, Zhu G, Cuscito C, Grano M, Colucci S, Iqbal J, Yuen T, Sun L, Zaidi M, Zallone A. Colaianni G, et al. Biochem Biophys Res Commun. 2011 Aug 5;411(3):512-5. doi: 10.1016/j.bbrc.2011.06.158. Epub 2011 Jun 29. Biochem Biophys Res Commun. 2011. PMID: 21741363