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Inducin Triggers LC3-Lipidation and ESCRT-Mediated Lysosomal Membrane Repair.
Corkery D, Ursu A, Lucas B, Grigalunas M, Kriegler S, Oliva R, Dec R, Koska S, Pahl A, Sievers S, Ziegler S, Winter R, Wu YW, Waldmann H. Corkery D, et al. Chembiochem. 2023 Dec 14;24(24):e202300579. doi: 10.1002/cbic.202300579. Epub 2023 Nov 7. Chembiochem. 2023. PMID: 37869939
Collective Synthesis of Sarpagine and Macroline Alkaloid-Inspired Compounds.
Aoyama H, Davies C, Liu J, Pahl A, Kirchhoff JL, Scheel R, Sievers S, Strohmann C, Grigalunas M, Waldmann H. Aoyama H, et al. Chemistry. 2024 Jan 22;30(5):e202303027. doi: 10.1002/chem.202303027. Epub 2023 Nov 29. Chemistry. 2024. PMID: 37755456
Design strategies that can access natural-product-like chemical space in an efficient manner may facilitate the discovery of biologically relevant compounds. We have employed a divergent intermediate strategy to construct an indole alkaloid-inspired compound collection der …
Design strategies that can access natural-product-like chemical space in an efficient manner may facilitate the discovery of biologic …