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Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation.
Kielczewski JL, Jarajapu YP, McFarland EL, Cai J, Afzal A, Li Calzi S, Chang KH, Lydic T, Shaw LC, Busik J, Hughes J, Cardounel AJ, Wilson K, Lyons TJ, Boulton ME, Mames RN, Chan-Ling T, Grant MB. Kielczewski JL, et al. Circ Res. 2009 Oct 23;105(9):897-905. doi: 10.1161/CIRCRESAHA.109.199059. Epub 2009 Sep 17. Circ Res. 2009. PMID: 19762684 Free PMC article.
Remodeling of retinal Fatty acids in an animal model of diabetes: a decrease in long-chain polyunsaturated fatty acids is associated with a decrease in fatty acid elongases Elovl2 and Elovl4.
Tikhonenko M, Lydic TA, Wang Y, Chen W, Opreanu M, Sochacki A, McSorley KM, Renis RL, Kern T, Jump DB, Reid GE, Busik JV. Tikhonenko M, et al. Diabetes. 2010 Jan;59(1):219-27. doi: 10.2337/db09-0728. Epub 2009 Oct 29. Diabetes. 2010. PMID: 19875612 Free PMC article.
N-3 polyunsaturated Fatty acids prevent diabetic retinopathy by inhibition of retinal vascular damage and enhanced endothelial progenitor cell reparative function.
Tikhonenko M, Lydic TA, Opreanu M, Li Calzi S, Bozack S, McSorley KM, Sochacki AL, Faber MS, Hazra S, Duclos S, Guberski D, Reid GE, Grant MB, Busik JV. Tikhonenko M, et al. PLoS One. 2013;8(1):e55177. doi: 10.1371/journal.pone.0055177. Epub 2013 Jan 29. PLoS One. 2013. PMID: 23383097 Free PMC article.