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Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung.
Proc Natl Acad Sci U S A. 2023 Jun 13;120(24):e2210113120. doi: 10.1073/pnas.2210113120. Epub 2023 Jun 6.
Proc Natl Acad Sci U S A. 2023.
PMID: 37279279
Free PMC article.
Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lung.
Frum T, Hsu PP, Hein RFC, Conchola AS, Zhang CJ, Utter OR, Anand A, Zhang Y, Clark SG, Glass I, Sexton JZ, Spence JR.
Frum T, et al.
NPJ Regen Med. 2023 Sep 9;8(1):48. doi: 10.1038/s41536-023-00325-z.
NPJ Regen Med. 2023.
PMID: 37689780
Free PMC article.
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Stable iPSC-derived NKX2-1+ lung bud tip progenitor organoids give rise to airway and alveolar cell types.
Hein RFC, Conchola AS, Fine AS, Xiao Z, Frum T, Brastrom LK, Akinwale MA, Childs CJ, Tsai YH, Holloway EM, Huang S, Mahoney J, Heemskerk I, Spence JR.
Hein RFC, et al.
Development. 2022 Oct 15;149(20):dev200693. doi: 10.1242/dev.200693. Epub 2022 Aug 30.
Development. 2022.
PMID: 36039869
Free PMC article.
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