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Page 1
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.
Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, Kampmann M, Bernstein BE, Hovestadt V, Gilbert LA, Weissman JS. Nuñez JK, et al. Cell. 2021 Apr 29;184(9):2503-2519.e17. doi: 10.1016/j.cell.2021.03.025. Epub 2021 Apr 9. Cell. 2021. PMID: 33838111 Free PMC article.
Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
Replogle JM, Saunders RA, Pogson AN, Hussmann JA, Lenail A, Guna A, Mascibroda L, Wagner EJ, Adelman K, Lithwick-Yanai G, Iremadze N, Oberstrass F, Lipson D, Bonnar JL, Jost M, Norman TM, Weissman JS. Replogle JM, et al. Cell. 2022 Jul 7;185(14):2559-2575.e28. doi: 10.1016/j.cell.2022.05.013. Epub 2022 Jun 9. Cell. 2022. PMID: 35688146 Free PMC article.
MTCH2 is a mitochondrial outer membrane protein insertase.
Guna A, Stevens TA, Inglis AJ, Replogle JM, Esantsi TK, Muthukumar G, Shaffer KCL, Wang ML, Pogson AN, Jones JJ, Lomenick B, Chou TF, Weissman JS, Voorhees RM. Guna A, et al. Science. 2022 Oct 21;378(6617):317-322. doi: 10.1126/science.add1856. Epub 2022 Oct 20. Science. 2022. PMID: 36264797 Free PMC article.
Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution.
Yang D, Jones MG, Naranjo S, Rideout WM 3rd, Min KHJ, Ho R, Wu W, Replogle JM, Page JL, Quinn JJ, Horns F, Qiu X, Chen MZ, Freed-Pastor WA, McGinnis CS, Patterson DM, Gartner ZJ, Chow ED, Bivona TG, Chan MM, Yosef N, Jacks T, Weissman JS. Yang D, et al. Cell. 2022 May 26;185(11):1905-1923.e25. doi: 10.1016/j.cell.2022.04.015. Epub 2022 May 5. Cell. 2022. PMID: 35523183 Free PMC article.
Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing.
Replogle JM, Norman TM, Xu A, Hussmann JA, Chen J, Cogan JZ, Meer EJ, Terry JM, Riordan DP, Srinivas N, Fiddes IT, Arthur JG, Alvarado LJ, Pfeiffer KA, Mikkelsen TS, Weissman JS, Adamson B. Replogle JM, et al. Nat Biotechnol. 2020 Aug;38(8):954-961. doi: 10.1038/s41587-020-0470-y. Epub 2020 Mar 30. Nat Biotechnol. 2020. PMID: 32231336 Free PMC article.
Microfluidics-free single-cell genomics with templated emulsification.
Clark IC, Fontanez KM, Meltzer RH, Xue Y, Hayford C, May-Zhang A, D'Amato C, Osman A, Zhang JQ, Hettige P, Ishibashi JSA, Delley CL, Weisgerber DW, Replogle JM, Jost M, Phong KT, Kennedy VE, Peretz CAC, Kim EA, Song S, Karlon W, Weissman JS, Smith CC, Gartner ZJ, Abate AR. Clark IC, et al. Nat Biotechnol. 2023 Nov;41(11):1557-1566. doi: 10.1038/s41587-023-01685-z. Epub 2023 Mar 6. Nat Biotechnol. 2023. PMID: 36879006 Free PMC article.
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress.
Do BT, Hsu PP, Vermeulen SY, Wang Z, Hirz T, Abbott KL, Aziz N, Replogle JM, Bjelosevic S, Paolino J, Nelson SA, Block S, Darnell AM, Ferreira R, Zhang H, Milosevic J, Schmidt DR, Chidley C, Harris IS, Weissman JS, Pikman Y, Stegmaier K, Cheloufi S, Su XA, Sykes DB, Vander Heiden MG. Do BT, et al. Dev Cell. 2024 Aug 19;59(16):2203-2221.e15. doi: 10.1016/j.devcel.2024.05.010. Epub 2024 May 31. Dev Cell. 2024. PMID: 38823395
12 results