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Global and tissue-specific aging effects on murine proteomes.
Keele GR, Zhang JG, Szpyt J, Korstanje R, Gygi SP, Churchill GA, Schweppe DK. Keele GR, et al. Cell Rep. 2023 Jul 25;42(7):112715. doi: 10.1016/j.celrep.2023.112715. Epub 2023 Jul 4. Cell Rep. 2023. PMID: 37405913 Free PMC article.
Multi-omics analysis identifies drivers of protein phosphorylation.
Zhang T, Keele GR, Gyuricza IG, Vincent M, Brunton C, Bell TA, Hock P, Shaw GD, Munger SC, de Villena FP, Ferris MT, Paulo JA, Gygi SP, Churchill GA. Zhang T, et al. Genome Biol. 2023 Mar 21;24(1):52. doi: 10.1186/s13059-023-02892-2. Genome Biol. 2023. PMID: 36944993 Free PMC article.
Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro.
Nemkov T, Key A, Stephenson D, Earley EJ, Keele GR, Hay A, Amireault P, Casimir M, Dussiot M, Dzieciatkowska M, Reisz JA, Deng X, Stone M, Kleinman S, Spitalnik SL, Hansen KC, Norris PJ, Churchill GA, Busch MP, Roubinian N, Page GP, Zimring JC, Arduini A, D'Alessandro A. Nemkov T, et al. Blood. 2024 Jun 13;143(24):2517-2533. doi: 10.1182/blood.2024023983. Blood. 2024. PMID: 38513237
Regulation of protein abundance in genetically diverse mouse populations.
Keele GR, Zhang T, Pham DT, Vincent M, Bell TA, Hock P, Shaw GD, Paulo JA, Munger SC, de Villena FP, Ferris MT, Gygi SP, Churchill GA. Keele GR, et al. Cell Genom. 2021 Oct 13;1(1):100003. doi: 10.1016/j.xgen.2021.100003. Epub 2021 Sep 3. Cell Genom. 2021. PMID: 36212994 Free PMC article.
A Bayesian model selection approach to mediation analysis.
Crouse WL, Keele GR, Gastonguay MS, Churchill GA, Valdar W. Crouse WL, et al. PLoS Genet. 2022 May 9;18(5):e1010184. doi: 10.1371/journal.pgen.1010184. eCollection 2022 May. PLoS Genet. 2022. PMID: 35533209 Free PMC article.
13 results