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Page 1
Platelet bioreactor-on-a-chip.
Thon JN, Mazutis L, Wu S, Sylman JL, Ehrlicher A, Machlus KR, Feng Q, Lu S, Lanza R, Neeves KB, Weitz DA, Italiano JE Jr. Thon JN, et al. Blood. 2014 Sep 18;124(12):1857-67. doi: 10.1182/blood-2014-05-574913. Blood. 2014. PMID: 25606631 Free PMC article.
Scalable generation of universal platelets from human induced pluripotent stem cells.
Feng Q, Shabrani N, Thon JN, Huo H, Thiel A, Machlus KR, Kim K, Brooks J, Li F, Luo C, Kimbrel EA, Wang J, Kim KS, Italiano J, Cho J, Lu SJ, Lanza R. Feng Q, et al. Stem Cell Reports. 2014 Nov 11;3(5):817-31. doi: 10.1016/j.stemcr.2014.09.010. Epub 2014 Oct 16. Stem Cell Reports. 2014. PMID: 25418726 Free PMC article.
CCL5 derived from platelets increases megakaryocyte proplatelet formation.
Machlus KR, Johnson KE, Kulenthirarajan R, Forward JA, Tippy MD, Soussou TS, El-Husayni SH, Wu SK, Wang S, Watnick RS, Italiano JE Jr, Battinelli EM. Machlus KR, et al. Blood. 2016 Feb 18;127(7):921-6. doi: 10.1182/blood-2015-05-644583. Epub 2015 Dec 8. Blood. 2016. PMID: 26647394 Free PMC article.
Proteasome function is required for platelet production.
Shi DS, Smith MC, Campbell RA, Zimmerman PW, Franks ZB, Kraemer BF, Machlus KR, Ling J, Kamba P, Schwertz H, Rowley JW, Miles RR, Liu ZJ, Sola-Visner M, Italiano JE Jr, Christensen H, Kahr WH, Li DY, Weyrich AS. Shi DS, et al. J Clin Invest. 2014 Sep;124(9):3757-66. doi: 10.1172/JCI75247. Epub 2014 Jul 25. J Clin Invest. 2014. PMID: 25061876 Free PMC article.
Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration.
Cloutier N, Allaeys I, Marcoux G, Machlus KR, Mailhot B, Zufferey A, Levesque T, Becker Y, Tessandier N, Melki I, Zhi H, Poirier G, Rondina MT, Italiano JE, Flamand L, McKenzie SE, Cote F, Nieswandt B, Khan WI, Flick MJ, Newman PJ, Lacroix S, Fortin PR, Boilard E. Cloutier N, et al. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1550-E1559. doi: 10.1073/pnas.1720553115. Epub 2018 Jan 31. Proc Natl Acad Sci U S A. 2018. PMID: 29386381 Free PMC article.
13 results