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Neurovascular coupling is optimized to compensate for the increase in proton production from nonoxidative glycolysis and glycogenolysis during brain activation and maintain homeostasis of pH, pCO2, and pO2.
J Neurochem. 2024 May;168(5):632-662. doi: 10.1111/jnc.15839. Epub 2023 Jun 21.
J Neurochem. 2024.
PMID: 37150946
Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission.
Rothman DL, Dienel GA, Behar KL, Hyder F, DiNuzzo M, Giove F, Mangia S.
Rothman DL, et al.
J Cereb Blood Flow Metab. 2022 May;42(5):844-860. doi: 10.1177/0271678X211064399. Epub 2022 Jan 7.
J Cereb Blood Flow Metab. 2022.
PMID: 34994222
Free PMC article.
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