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The Initiation of Eukaryotic DNA Replication.
Costa A, Diffley JFX. Costa A, et al. Annu Rev Biochem. 2022 Jun 21;91:107-131. doi: 10.1146/annurev-biochem-072321-110228. Epub 2022 Mar 23. Annu Rev Biochem. 2022. PMID: 35320688 Review.
The mechanism of eukaryotic CMG helicase activation.
Douglas ME, Ali FA, Costa A, Diffley JFX. Douglas ME, et al. Nature. 2018 Mar 8;555(7695):265-268. doi: 10.1038/nature25787. Epub 2018 Feb 28. Nature. 2018. PMID: 29489749 Free PMC article.
A Structure-Based Mechanism for DNA Entry into the Cohesin Ring.
Higashi TL, Eickhoff P, Sousa JS, Locke J, Nans A, Flynn HR, Snijders AP, Papageorgiou G, O'Reilly N, Chen ZA, O'Reilly FJ, Rappsilber J, Costa A, Uhlmann F. Higashi TL, et al. Mol Cell. 2020 Sep 17;79(6):917-933.e9. doi: 10.1016/j.molcel.2020.07.013. Epub 2020 Aug 4. Mol Cell. 2020. PMID: 32755595 Free PMC article.
A combined structural and biochemical approach reveals translocation and stalling of UvrB on the DNA lesion as a mechanism of damage verification in bacterial nucleotide excision repair.
Jaciuk M, Swuec P, Gaur V, Kasprzak JM, Renault L, Dobrychłop M, Nirwal S, Bujnicki JM, Costa A, Nowotny M. Jaciuk M, et al. DNA Repair (Amst). 2020 Jan;85:102746. doi: 10.1016/j.dnarep.2019.102746. Epub 2019 Nov 6. DNA Repair (Amst). 2020. PMID: 31739207 Free PMC article.
SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity.
Rosa A, Pye VE, Graham C, Muir L, Seow J, Ng KW, Cook NJ, Rees-Spear C, Parker E, Dos Santos MS, Rosadas C, Susana A, Rhys H, Nans A, Masino L, Roustan C, Christodoulou E, Ulferts R, Wrobel AG, Short CE, Fertleman M, Sanders RW, Heaney J, Spyer M, Kjær S, Riddell A, Malim MH, Beale R, MacRae JI, Taylor GP, Nastouli E, van Gils MJ, Rosenthal PB, Pizzato M, McClure MO, Tedder RS, Kassiotis G, McCoy LE, Doores KJ, Cherepanov P. Rosa A, et al. Sci Adv. 2021 May 28;7(22):eabg7607. doi: 10.1126/sciadv.abg7607. Print 2021 May. Sci Adv. 2021. PMID: 33888467 Free PMC article.
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