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2021 1
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Page 1
Glymphatic system dysfunction predicts amyloid deposition, neurodegeneration, and clinical progression in Alzheimer's disease.
Huang SY, Zhang YR, Guo Y, Du J, Ren P, Wu BS, Feng JF; Alzheimer's Disease Neuroimaging Initiative; Cheng W, Yu JT. Huang SY, et al. Alzheimers Dement. 2024 May;20(5):3251-3269. doi: 10.1002/alz.13789. Epub 2024 Mar 19. Alzheimers Dement. 2024. PMID: 38501315 Free PMC article.
Furthermore, the associations of the ALPS index with cognitive decline were fully mediated by amyloid PET and brain atrophy. DISCUSSION: Glymphatic failure may precede amyloid pathology, and predicts amyloid deposition, neurodegeneration, and clinical progression in AD. .. …
Furthermore, the associations of the ALPS index with cognitive decline were fully mediated by amyloid PET and brain atrophy. DISCUSSI …
Circulating metabolites and risk of incident dementia: A prospective cohort study.
Huang SY, Zhang YR, Yang L, Li YZ, Wu BS, Chen SD, Feng JF, Dong Q, Cheng W, Yu JT. Huang SY, et al. J Neurochem. 2023 Dec;167(5):668-679. doi: 10.1111/jnc.15997. Epub 2023 Oct 31. J Neurochem. 2023. PMID: 37908051
Identifying circulating metabolites associated with dementia, cognition, and brain volume may improve the understanding of dementia pathogenesis and provide novel insights for preventive and therapeutic interventions. ...Among them, the cholesterol percentage in L-LDL (L-L …
Identifying circulating metabolites associated with dementia, cognition, and brain volume may improve the understanding of dementia p …
Bilateral gene therapy in children with autosomal recessive deafness 9: single-arm trial results.
Wang H, Chen Y, Lv J, Cheng X, Cao Q, Wang D, Zhang L, Zhu B, Shen M, Xu C, Xun M, Wang Z, Tang H, Hu S, Cui C, Jiang L, Yin Y, Guo L, Zhou Y, Han L, Gao Z, Zhang J, Yu S, Gao K, Wang J, Chen B, Wang W, Chen ZY, Li H, Shu Y. Wang H, et al. Nat Med. 2024 Jul;30(7):1898-1904. doi: 10.1038/s41591-024-03023-5. Epub 2024 Jun 5. Nat Med. 2024. PMID: 38839897 Free PMC article. Clinical Trial.
Maternal sevoflurane exposure increases the epilepsy susceptibility of adolescent offspring by interrupting interneuron development.
Liang X, Jiang M, Xu H, Tang T, Shi X, Dong Y, Xiao L, Xie Y, Fang F, Cang J. Liang X, et al. BMC Med. 2023 Dec 21;21(1):510. doi: 10.1186/s12916-023-03210-0. BMC Med. 2023. PMID: 38129829 Free PMC article.
BACKGROUND: Exposure to general anesthesia influences neuronal functions during brain development. Recently, interneurons were found to be involved in developmental neurotoxicity by anesthetic exposure. ...
BACKGROUND: Exposure to general anesthesia influences neuronal functions during brain development. Recently, interneurons were found …
Genome-wide meta-analysis identifies ancestry-specific loci for Alzheimer's disease.
Ge YJ, Chen SD, Wu BS, Zhang YR, Wang J, He XY, Liu WS, Chen YL, Ou YN, Shen XN, Huang YY, Gan YH, Yang L, Ma LZ, Ma YH, Chen KL, Chen SF, Cui M, Tan L, Dong Q, Zhao QH, Wang YJ, Jia JP, Yu JT. Ge YJ, et al. Alzheimers Dement. 2024 Sep;20(9):6243-6256. doi: 10.1002/alz.14121. Epub 2024 Jul 18. Alzheimers Dement. 2024. PMID: 39023044 Free PMC article.
Incremental value of amyloid PET in a tertiary memory clinic setting in China.
Chen KL, Wang MY, Wu J, Zuo CT, Huang YY, Wang WY, Zhao M, Zhang YR, Zhang X, Chen SF, Liu WS, Li MM, Ge JJ, Ma XX, Wang J, Zheng L, Guan YH, Dong Q, Cui M, Xie F, Zhao QH, Yu JT. Chen KL, et al. Alzheimers Dement. 2024 Apr;20(4):2516-2525. doi: 10.1002/alz.13728. Epub 2024 Feb 8. Alzheimers Dement. 2024. PMID: 38329281 Free PMC article.
Socioeconomic status, lifestyle and risk of incident dementia: a prospective cohort study of 276730 participants.
Ou YN, Zhang YB, Li YZ, Huang SY, Zhang W, Deng YT, Wu BS, Tan L, Dong Q, Pan A, Chen RJ, Feng JF, Smith AD, Cheng W, Yu JT. Ou YN, et al. Geroscience. 2024 Apr;46(2):2265-2279. doi: 10.1007/s11357-023-00994-0. Epub 2023 Nov 6. Geroscience. 2024. PMID: 37926784 Free PMC article.
This study aimed to detect the joint and interactive associations of socioeconomic status (SES) and lifestyle factors with incident dementia risk, and the underlying brain imaging alterations. ...The combination of high SES and healthy lifestyle was positively assoc …
This study aimed to detect the joint and interactive associations of socioeconomic status (SES) and lifestyle factors with incident d …
Associations between adiposity and white matter hyperintensities: Cross-sectional and longitudinal analyses of 34,653 participants.
Wang RZ, Deng YT, Zhang W, Ning J, Li HQ, Feng JF, Cheng W, Yu JT. Wang RZ, et al. Hum Brain Mapp. 2024 Jan;45(1):e26560. doi: 10.1002/hbm.26560. Hum Brain Mapp. 2024. PMID: 38224536 Free PMC article.
The detrimental effects of adiposity on WMH occurred throughout midlife and in the elderly and may still exist after changes in obesity status....
The detrimental effects of adiposity on WMH occurred throughout midlife and in the elderly and may still exist after changes in obesity s …
22 results