Screening Methods for Cervical Cancer

ChemMedChem. 2024 Aug 19;19(16):e202400021. doi: 10.1002/cmdc.202400021. Epub 2024 Jun 19.

Abstract

Cervical cancer seriously affects the health of women worldwide. Persistent infection of high-risk HPV (Human Papilloma Virus) can lead to cervical cancer. There is a great need for timely and efficient screening methods for cervical cancer. The current screening methods for cervical cancer are mainly based on cervical cytology and HPV testing. Cervical cytology is made of Pap smear and liquid-based cytology, while HPV testing is based on immunological and nucleic acid level detection methods. This review introduces cervical cancer screening methods based on cytology and human papillomavirus testing in detail. The advantages and limitations of the screening methods are also summarized and compared.

Keywords: HPV testing; cervical cancer; cytology; screening.

Publication types

  • Review

MeSH terms

  • Early Detection of Cancer*
  • Female
  • Humans
  • Papillomaviridae / isolation & purification
  • Papillomavirus Infections / diagnosis
  • Uterine Cervical Neoplasms* / diagnosis