GM067657/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2007	2
2008	3
2010	1
2011	1
2012	1
2013	1
2014	1
2015	1
2016	1
2018	1
2019	1
2021	1
2024	0

1

Isoform-selective histone deacetylase inhibitors.

Bieliauskas AV, Pflum MK. Bieliauskas AV, et al. Chem Soc Rev. 2008 Jul;37(7):1402-13. doi: 10.1039/b703830p. Epub 2008 May 8. Chem Soc Rev. 2008. PMID: 18568166 Free PMC article. Review.

2

HDAC1 Substrate Profiling Using Proteomics-Based Substrate Trapping.

Nalawansha DA, Zhang Y, Herath K, Pflum MKH. Nalawansha DA, et al. ACS Chem Biol. 2018 Dec 21;13(12):3315-3324. doi: 10.1021/acschembio.8b00737. Epub 2018 Dec 10. ACS Chem Biol. 2018. PMID: 30421914 Free PMC article.

3

A histone deacetylase-dependent screen in yeast.

Weerasinghe SV, Wambua M, Pflum MK. Weerasinghe SV, et al. Bioorg Med Chem. 2010 Nov 1;18(21):7586-92. doi: 10.1016/j.bmc.2010.08.045. Epub 2010 Sep 20. Bioorg Med Chem. 2010. PMID: 20863708 Free PMC article.

4

Biotinylated phosphoproteins from kinase-catalyzed biotinylation are stable to phosphatases: implications for phosphoproteomics.

Senevirathne C, Pflum MK. Senevirathne C, et al. Chembiochem. 2013 Feb 11;14(3):381-7. doi: 10.1002/cbic.201200626. Epub 2013 Jan 17. Chembiochem. 2013. PMID: 23335220 Free PMC article.

5

HDAC6 Substrate Discovery Using Proteomics-Based Substrate Trapping: HDAC6 Deacetylates PRMT5 to Influence Methyltransferase Activity.

Gomes ID, Ariyaratne UV, Pflum MKH. Gomes ID, et al. ACS Chem Biol. 2021 Aug 20;16(8):1435-1444. doi: 10.1021/acschembio.1c00303. Epub 2021 Jul 27. ACS Chem Biol. 2021. PMID: 34314149 Free PMC article.

6

The structural requirements of histone deacetylase inhibitors: suberoylanilide hydroxamic acid analogs modified at the C6 position.

Choi SE, Pflum MK. Choi SE, et al. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7084-6. doi: 10.1016/j.bmcl.2012.09.093. Epub 2012 Oct 2. Bioorg Med Chem Lett. 2012. PMID: 23089527 Free PMC article.

7

Optimal Substrate-Trapping Mutants to Discover Substrates of HDAC1.

Gomes ID, Pflum MKH. Gomes ID, et al. Chembiochem. 2019 Jun 3;20(11):1444-1449. doi: 10.1002/cbic.201800797. Epub 2019 Apr 25. Chembiochem. 2019. PMID: 30701667 Free PMC article.

8

A comparative study of ATP analogs for phosphorylation-dependent kinase-substrate crosslinking.

Garre S, Senevirathne C, Pflum MK. Garre S, et al. Bioorg Med Chem. 2014 Mar 1;22(5):1620-5. doi: 10.1016/j.bmc.2014.01.034. Epub 2014 Jan 30. Bioorg Med Chem. 2014. PMID: 24529309 Free PMC article.

9

Histone deacetylase 1 phosphorylation at S421 and S423 is constitutive in vivo, but dispensable in vitro.

Karwowska-Desaulniers P, Ketko A, Kamath N, Pflum MK. Karwowska-Desaulniers P, et al. Biochem Biophys Res Commun. 2007 Sep 21;361(2):349-55. doi: 10.1016/j.bbrc.2007.06.167. Epub 2007 Jul 16. Biochem Biophys Res Commun. 2007. PMID: 17643391

10

Structural requirements of HDAC inhibitors: SAHA analogs functionalized adjacent to the hydroxamic acid.

Bieliauskas AV, Weerasinghe SV, Pflum MK. Bieliauskas AV, et al. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2216-9. doi: 10.1016/j.bmcl.2007.01.117. Epub 2007 Feb 8. Bioorg Med Chem Lett. 2007. PMID: 17307359 Free PMC article.

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