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Super-enhancer-driven IRF2BP2 enhances ALK activity and promotes neuroblastoma cell proliferation.
Neuro Oncol. 2024 Oct 3;26(10):1878-1894. doi: 10.1093/neuonc/noae109.
Neuro Oncol. 2024.
PMID: 38864832
The BET inhibitor GNE-987 effectively induces anti-cancer effects in T-cell acute lymphoblastic leukemia by targeting enhancer regulated genes.
Yu J, Yang Y, Zhou R, Tao Y, Zhu F, Jiao W, Zhang Z, Ji T, Li T, Fang F, Xie Y, Wu D, Zhuo R, Li X, Chen Y, Yin H, Wang J, Pan J.
Yu J, et al.
Carcinogenesis. 2024 Jun 10;45(6):424-435. doi: 10.1093/carcin/bgae006.
Carcinogenesis. 2024.
PMID: 38302114
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Super-Enhancer-Driven IRF2BP2 is Activated by Master Transcription Factors and Sustains T-ALL Cell Growth and Survival.
Yu J, Zhang Z, Chen Y, Wang J, Li G, Tao Y, Zhang Y, Yang Y, Zhang C, Li T, Cheng J, Ji T, Wei Z, Wang W, Fang F, Jiang W, Chu P, Yin H, Wu D, Li X, Wang X, Fan JJ, Hu S, Zhu ZH, Wu S, Lu J, Pan J.
Yu J, et al.
Adv Sci (Weinh). 2024 Oct 25:e2407113. doi: 10.1002/advs.202407113. Online ahead of print.
Adv Sci (Weinh). 2024.
PMID: 39454110
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