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A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2.
Hassan AO, Kafai NM, Dmitriev IP, Fox JM, Smith BK, Harvey IB, Chen RE, Winkler ES, Wessel AW, Case JB, Kashentseva E, McCune BT, Bailey AL, Zhao H, VanBlargan LA, Dai YN, Ma M, Adams LJ, Shrihari S, Danis JE, Gralinski LE, Hou YJ, Schäfer A, Kim AS, Keeler SP, Weiskopf D, Baric RS, Holtzman MJ, Fremont DH, Curiel DT, Diamond MS. Hassan AO, et al. Cell. 2020 Oct 1;183(1):169-184.e13. doi: 10.1016/j.cell.2020.08.026. Epub 2020 Aug 19. Cell. 2020. PMID: 32931734 Free PMC article.
prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
Dowd KA, Sirohi D, Speer SD, VanBlargan LA, Chen RE, Mukherjee S, Whitener BM, Govero J, Aleshnick M, Larman B, Sukupolvi-Petty S, Sevvana M, Miller AS, Klose T, Zheng A, Koenig S, Kielian M, Kuhn RJ, Diamond MS, Pierson TC. Dowd KA, et al. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2218899120. doi: 10.1073/pnas.2218899120. Epub 2023 Jan 13. Proc Natl Acad Sci U S A. 2023. PMID: 36638211 Free PMC article.
Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope.
Kim AS, Kafai NM, Winkler ES, Gilliland TC Jr, Cottle EL, Earnest JT, Jethva PN, Kaplonek P, Shah AP, Fong RH, Davidson E, Malonis RJ, Quiroz JA, Williamson LE, Vang L, Mack M, Crowe JE Jr, Doranz BJ, Lai JR, Alter G, Gross ML, Klimstra WB, Fremont DH, Diamond MS. Kim AS, et al. Cell. 2021 Aug 19;184(17):4414-4429.e19. doi: 10.1016/j.cell.2021.07.006. Cell. 2021. PMID: 34416146 Free PMC article.
Structural Basis of Zika Virus-Specific Antibody Protection.
Zhao H, Fernandez E, Dowd KA, Speer SD, Platt DJ, Gorman MJ, Govero J, Nelson CA, Pierson TC, Diamond MS, Fremont DH. Zhao H, et al. Cell. 2016 Aug 11;166(4):1016-1027. doi: 10.1016/j.cell.2016.07.020. Epub 2016 Jul 27. Cell. 2016. PMID: 27475895 Free PMC article.
An intranasal vaccine durably protects against SARS-CoV-2 variants in mice.
Hassan AO, Shrihari S, Gorman MJ, Ying B, Yuan D, Raju S, Chen RE, Dmitriev IP, Kashentseva E, Adams LJ, Mann C, Davis-Gardner ME, Suthar MS, Shi PY, Saphire EO, Fremont DH, Curiel DT, Alter G, Diamond MS. Hassan AO, et al. Cell Rep. 2021 Jul 27;36(4):109452. doi: 10.1016/j.celrep.2021.109452. Epub 2021 Jul 10. Cell Rep. 2021. PMID: 34289385 Free PMC article.
A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques.
Hassan AO, Feldmann F, Zhao H, Curiel DT, Okumura A, Tang-Huau TL, Case JB, Meade-White K, Callison J, Chen RE, Lovaglio J, Hanley PW, Scott DP, Fremont DH, Feldmann H, Diamond MS. Hassan AO, et al. Cell Rep Med. 2021 Apr 20;2(4):100230. doi: 10.1016/j.xcrm.2021.100230. Epub 2021 Mar 18. Cell Rep Med. 2021. PMID: 33754147 Free PMC article.
Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe JE Jr. Powell LA, et al. Cell Host Microbe. 2020 Nov 11;28(5):699-711.e7. doi: 10.1016/j.chom.2020.07.008. Epub 2020 Aug 11. Cell Host Microbe. 2020. PMID: 32783883 Free PMC article.
23 results