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VEGFR3 tyrosine kinase inhibition aggravates cisplatin nephrotoxicity.
Black LM, Farrell ER, Barwinska D, Osis G, Zmijewska AA, Traylor AM, Esman SK, Bolisetty S, Whipple G, Kamocka MM, Winfree S, Spangler DR, Khan S, Zarjou A, El-Achkar TM, Agarwal A. Black LM, et al. Am J Physiol Renal Physiol. 2021 Dec 1;321(6):F675-F688. doi: 10.1152/ajprenal.00186.2021. Epub 2021 Oct 18. Am J Physiol Renal Physiol. 2021. PMID: 34658261 Free PMC article.
The kidney protects against sepsis by producing systemic uromodulin.
LaFavers KA, Hage CA, Gaur V, Micanovic R, Hato T, Khan S, Winfree S, Doshi S, Moorthi RN, Twigg H, Wu XR, Dagher PC, Srour EF, El-Achkar TM. LaFavers KA, et al. Am J Physiol Renal Physiol. 2022 Aug 1;323(2):F212-F226. doi: 10.1152/ajprenal.00146.2022. Epub 2022 Jun 27. Am J Physiol Renal Physiol. 2022. PMID: 35759740 Free PMC article.
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