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Potential role of blood pressure variability and plasma neurofilament light in the mechanism of comorbidity between Alzheimer's disease and cerebral small vessel disease.
Li Q, Su S, Feng Y, Jia M, Zhan J, Liao Z, Li J, Li X; Alzheimer's Disease Neuroimaging Initiative. Li Q, et al. Alzheimers Dement. 2024 Jul;20(7):4891-4902. doi: 10.1002/alz.14056. Epub 2024 Jun 19. Alzheimers Dement. 2024. PMID: 38895921 Free PMC article.
INTRODUCTION: Long-term blood pressure variability (BPV) and plasma neurofilament light (pNfL) have been identified as potential biomarkers for Alzheimer's disease (AD) and cerebral small vessel disease (CSVD). However, the relationship between BPV, pN …
INTRODUCTION: Long-term blood pressure variability (BPV) and plasma neurofilament light (pNfL) have been identified as potential biomarkers …
Stress testing the Centiloid: Precision and variability of PET quantification of amyloid pathology.
Shekari M, Vállez García D, Collij LE, Altomare D, Heeman F, Pemberton H, Roé Vellvé N, Bullich S, Buckley C, Stephens A, Farrar G, Frisoni G, Klunk WE, Barkhof F, Gispert JD; ADNI and the AMYPAD consortium. Shekari M, et al. Alzheimers Dement. 2024 Aug;20(8):5102-5113. doi: 10.1002/alz.13883. Epub 2024 Jul 4. Alzheimers Dement. 2024. PMID: 38961808 Free PMC article.
METHODS: We included 533 participants from AMYloid imaging to Prevent Alzheimer's Disease (AMYPAD DPMS) and Alzheimer's Disease Neuroimaging Initiative (ADNI) cohorts. ...Confidence intervals should be considered when operationalizing CL …
METHODS: We included 533 participants from AMYloid imaging to Prevent Alzheimer's Disease (AMYPAD DPMS) and Alzheime …
Study partner-reported decline identifies cognitive decline and dementia risk.
Nosheny RL, Jin C, Neuhaus J, Insel PS, Mackin RS, Weiner MW; Alzheimer’s Disease Neuroimaging Initiative investigators. Nosheny RL, et al. Ann Clin Transl Neurol. 2019 Dec;6(12):2448-2459. doi: 10.1002/acn3.50938. Epub 2019 Nov 13. Ann Clin Transl Neurol. 2019. PMID: 31721455 Free PMC article.
OBJECTIVE: Identifying individuals at risk for cognitive decline, Mild Cognitive Impairment (MCI), and dementia due to Alzheimer's disease (AD) is a critical need. Functional decline is associated with risk and can be efficiently assessed by participants and …
OBJECTIVE: Identifying individuals at risk for cognitive decline, Mild Cognitive Impairment (MCI), and dementia due to Alzheimer's …
Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.
Ray NR, Kunkle BW, Hamilton-Nelson K, Kurup JT, Rajabli F, Qiao M, Vardarajan BN, Cosacak MI, Kizil C, Jean-Francois M, Cuccaro M, Reyes-Dumeyer D, Cantwell L, Kuzma A, Vance JM, Gao S, Hendrie HC, Baiyewu O, Ogunniyi A, Akinyemi RO; Alzheimer's Disease Genetics Consortium; Lee WP, Martin ER, Wang LS, Beecham GW, Bush WS, Xu W, Jin F, Wang L, Farrer LA, Haines JL, Byrd GS, Schellenberg GD, Mayeux R, Pericak-Vance MA, Reitz C. Ray NR, et al. Alzheimers Dement. 2024 Aug;20(8):5247-5261. doi: 10.1002/alz.13880. Epub 2024 Jul 3. Alzheimers Dement. 2024. PMID: 38958117 Free PMC article.
HIGHLIGHTS: Genetic ancestry significantly impacts risk of Alzheimer's Disease (AD). Although individuals of African ancestry are twice as likely to develop AD, they are vastly underrepresented in AD genomics studies. The Alzheimer's Disease …
HIGHLIGHTS: Genetic ancestry significantly impacts risk of Alzheimer's Disease (AD). Although individuals of African an …
Clusters of cognitive performance predict long-term cognitive impairment in elderly patients with subjective memory complaints and healthy controls.
Jiménez-Huete A, Villino-Rodríguez R, Ríos-Rivera MM, Rognoni T, Montoya-Murillo G, Arrondo C, Zapata C, Rodríguez-Oroz MC, Riverol M; Alzheimer's Disease Neuroimaging Initiative. Jiménez-Huete A, et al. Alzheimers Dement. 2024 Jul;20(7):4702-4716. doi: 10.1002/alz.13903. Epub 2024 May 23. Alzheimers Dement. 2024. PMID: 38779851 Free PMC article.
This cluster shows a pattern of biomarkers consistent with incipient Alzheimer's disease pathology. The same cognitive cluster structure is found in healthy controls. ...
This cluster shows a pattern of biomarkers consistent with incipient Alzheimer's disease pathology. The same cognitive …