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2019 1
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Page 1
Developing dietary interventions as therapy for cancer.
Taylor SR, Falcone JN, Cantley LC, Goncalves MD. Taylor SR, et al. Nat Rev Cancer. 2022 Aug;22(8):452-466. doi: 10.1038/s41568-022-00485-y. Epub 2022 May 25. Nat Rev Cancer. 2022. PMID: 35614234 Review.
High-fructose corn syrup enhances intestinal tumor growth in mice.
Goncalves MD, Lu C, Tutnauer J, Hartman TE, Hwang SK, Murphy CJ, Pauli C, Morris R, Taylor S, Bosch K, Yang S, Wang Y, Van Riper J, Lekaye HC, Roper J, Kim Y, Chen Q, Gross SS, Rhee KY, Cantley LC, Yun J. Goncalves MD, et al. Science. 2019 Mar 22;363(6433):1345-1349. doi: 10.1126/science.aat8515. Science. 2019. PMID: 30898933 Free PMC article.
Dietary fructose improves intestinal cell survival and nutrient absorption.
Taylor SR, Ramsamooj S, Liang RJ, Katti A, Pozovskiy R, Vasan N, Hwang SK, Nahiyaan N, Francoeur NJ, Schatoff EM, Johnson JL, Shah MA, Dannenberg AJ, Sebra RP, Dow LE, Cantley LC, Rhee KY, Goncalves MD. Taylor SR, et al. Nature. 2021 Sep;597(7875):263-267. doi: 10.1038/s41586-021-03827-2. Epub 2021 Aug 18. Nature. 2021. PMID: 34408323 Free PMC article.
TIMP1 is an early biomarker for detection and prognosis of lung cancer.
Dantas E, Murthy A, Ahmed T, Ahmed M, Ramsamooj S, Hurd MA, Lam T, Malbari M, Agrusa C, Elemento O, Zhang C, Pappin DJ, McGraw TE, Stiles BM, Altorki NK, Goncalves MD. Dantas E, et al. Clin Transl Med. 2023 Oct;13(10):e1391. doi: 10.1002/ctm2.1391. Clin Transl Med. 2023. PMID: 37759102 Free PMC article.
Epinephrine inhibits PI3Kα via the Hippo kinases.
Lin TY, Ramsamooj S, Perrier T, Liberatore K, Lantier L, Vasan N, Karukurichi K, Hwang SK, Kesicki EA, Kastenhuber ER, Wiederhold T, Yaron TM, Huntsman EM, Zhu M, Ma Y, Paddock MN, Zhang G, Hopkins BD, McGuinness O, Schwartz RE, Ersoy BA, Cantley LC, Johnson JL, Goncalves MD. Lin TY, et al. Cell Rep. 2023 Dec 26;42(12):113535. doi: 10.1016/j.celrep.2023.113535. Epub 2023 Dec 4. Cell Rep. 2023. PMID: 38060450 Free PMC article.
Engineered diets to improve cancer outcomes.
Goncalves MD, Maddocks OD. Goncalves MD, et al. Curr Opin Biotechnol. 2021 Aug;70:29-35. doi: 10.1016/j.copbio.2020.10.007. Epub 2020 Nov 21. Curr Opin Biotechnol. 2021. PMID: 33232844 Free PMC article. Review.
Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer.
Langer HT, Ramsamooj S, Dantas E, Murthy A, Ahmed M, Hwang SK, Grover R, Pozovskiy R, Liang RJ, Queiroz AL, Brown JC, White EP, Janowitz T, Goncalves AMD. Langer HT, et al. bioRxiv [Preprint]. 2023 Aug 2:2023.07.31.551241. doi: 10.1101/2023.07.31.551241. bioRxiv. 2023. Update in: Acta Physiol (Oxf). 2024 Aug;240(8):e14167. doi: 10.1111/apha.14167 PMID: 37577571 Free PMC article. Updated. Preprint.
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