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Myocardial brain-derived neurotrophic factor regulates cardiac bioenergetics through the transcription factor Yin Yang 1.
Yang X, Zhang M, Xie B, Peng Z, Manning JR, Zimmerman R, Wang Q, Wei AC, Khalifa M, Reynolds M, Jin J, Om M, Zhu G, Bedja D, Jiang H, Jurczak M, Shiva S, Scott I, O'Rourke B, Kass DA, Paolocci N, Feng N. Yang X, et al. Cardiovasc Res. 2023 Mar 31;119(2):571-586. doi: 10.1093/cvr/cvac096. Cardiovasc Res. 2023. PMID: 35704040 Free PMC article.
CaMKII exacerbates heart failure progression by activating class I HDACs.
Zhang M, Yang X, Zimmerman RJ, Wang Q, Ross MA, Granger JM, Luczak ED, Bedja D, Jiang H, Feng N. Zhang M, et al. J Mol Cell Cardiol. 2020 Dec;149:73-81. doi: 10.1016/j.yjmcc.2020.09.007. Epub 2020 Sep 22. J Mol Cell Cardiol. 2020. PMID: 32971072 Free PMC article.
BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.
Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, Wendell SG, Mullett SJ, Sembrat J, Rojas M, Khan OF, Dahlman JE, Sugahara M, Kagiyama N, Satoh T, Zhang M, Feng N, Gorcsan J 3rd, Vargas SO, Haley KJ, Kumar R, Graham BB, Langer R, Anderson DG, Wang B, Shiva S, Bertero T, Chan SY. Yu Q, et al. Circulation. 2019 May 7;139(19):2238-2255. doi: 10.1161/CIRCULATIONAHA.118.035889. Circulation. 2019. PMID: 30759996 Free PMC article.
Reduced acetylation of TFAM promotes bioenergetic dysfunction in the failing heart.
Zhang M, Feng N, Peng Z, Thapa D, Stoner MW, Manning JR, McTiernan CF, Yang X, Jurczak MJ, Guimaraes D, Rao K, Shiva S, Kaufman BA, Sack MN, Scott I. Zhang M, et al. iScience. 2023 May 23;26(6):106942. doi: 10.1016/j.isci.2023.106942. eCollection 2023 Jun 16. iScience. 2023. PMID: 37305705 Free PMC article.