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Page 1
Janus Kinase Inhibition in the Aicardi-Goutières Syndrome.
Vanderver A, Adang L, Gavazzi F, McDonald K, Helman G, Frank DB, Jaffe N, Yum SW, Collins A, Keller SR, Lebon P, Meritet JF, Rhee J, Takanohashi A, Armangue T, Ulrick N, Sherbini O, Koh J, Peer K, Besnier C, Scher C, Boyle K, Dubbs H, Kramer-Golinkoff J, Pizzino A, Woidill S, Shults J. Vanderver A, et al. N Engl J Med. 2020 Sep 3;383(10):986-989. doi: 10.1056/NEJMc2001362. N Engl J Med. 2020. PMID: 32877590 Free PMC article. Clinical Trial. No abstract available.
Age-dependent alveolar epithelial plasticity orchestrates lung homeostasis and regeneration.
Penkala IJ, Liberti DC, Pankin J, Sivakumar A, Kremp MM, Jayachandran S, Katzen J, Leach JP, Windmueller R, Stolz K, Morley MP, Babu A, Zhou S, Frank DB, Morrisey EE. Penkala IJ, et al. Cell Stem Cell. 2021 Oct 7;28(10):1775-1789.e5. doi: 10.1016/j.stem.2021.04.026. Epub 2021 May 10. Cell Stem Cell. 2021. PMID: 33974915 Free PMC article.
Hedgehog and WNT Signaling Hubs in Tracheal Morphogenesis.
Frank DB, Morrisey EE. Frank DB, et al. Am J Respir Crit Care Med. 2019 Nov 15;200(10):1202-1204. doi: 10.1164/rccm.201907-1285ED. Am J Respir Crit Care Med. 2019. PMID: 31291547 Free PMC article. No abstract available.
Circadian regulation of lung repair and regeneration.
Naik A, Forrest KM, Paul O, Issah Y, Valekunja UK, Tang SY, Reddy AB, Hennessy EJ, Brooks TG, Chaudhry F, Babu A, Morley M, Zepp JA, Grant GR, FitzGerald GA, Sehgal A, Worthen GS, Frank DB, Morrisey EE, Sengupta S. Naik A, et al. JCI Insight. 2023 Aug 22;8(16):e164720. doi: 10.1172/jci.insight.164720. JCI Insight. 2023. PMID: 37463053 Free PMC article.
Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes.
Shah PP, Lv W, Rhoades JH, Poleshko A, Abbey D, Caporizzo MA, Linares-Saldana R, Heffler JG, Sayed N, Thomas D, Wang Q, Stanton LJ, Bedi K, Morley MP, Cappola TP, Owens AT, Margulies KB, Frank DB, Wu JC, Rader DJ, Yang W, Prosser BL, Musunuru K, Jain R. Shah PP, et al. Cell Stem Cell. 2021 May 6;28(5):938-954.e9. doi: 10.1016/j.stem.2020.12.016. Epub 2021 Feb 1. Cell Stem Cell. 2021. PMID: 33529599 Free PMC article.
CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth.
Chandrasekaran P, Negretti NM, Sivakumar A, Liberti DC, Wen H, Peers de Nieuwburgh M, Wang JY, Michki NS, Chaudhry FN, Kaur S, Lu M, Jin A, Zepp JA, Young LR, Sucre JMS, Frank DB. Chandrasekaran P, et al. Development. 2022 Nov 1;149(21):dev200909. doi: 10.1242/dev.200909. Epub 2022 Oct 31. Development. 2022. PMID: 36239312 Free PMC article.
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