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2020 2
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Single-cell transcriptomics reveals skewed cellular communication and phenotypic shift in pulmonary artery remodeling.
Crnkovic S, Valzano F, Fließer E, Gindlhuber J, Thekkekara Puthenparampil H, Basil M, Morley MP, Katzen J, Gschwandtner E, Klepetko W, Cantu E, Wolinski H, Olschewski H, Lindenmann J, Zhao YY, Morrisey EE, Marsh LM, Kwapiszewska G. Crnkovic S, et al. JCI Insight. 2022 Oct 24;7(20):e153471. doi: 10.1172/jci.insight.153471. JCI Insight. 2022. PMID: 36099047 Free PMC article.
Human distal airways contain a multipotent secretory cell that can regenerate alveoli.
Basil MC, Cardenas-Diaz FL, Kathiriya JJ, Morley MP, Carl J, Brumwell AN, Katzen J, Slovik KJ, Babu A, Zhou S, Kremp MM, McCauley KB, Li S, Planer JD, Hussain SS, Liu X, Windmueller R, Ying Y, Stewart KM, Oyster M, Christie JD, Diamond JM, Engelhardt JF, Cantu E, Rowe SM, Kotton DN, Chapman HA, Morrisey EE. Basil MC, et al. Nature. 2022 Apr;604(7904):120-126. doi: 10.1038/s41586-022-04552-0. Epub 2022 Mar 30. Nature. 2022. PMID: 35355013 Free PMC article.
Age-dependent alveolar epithelial plasticity orchestrates lung homeostasis and regeneration.
Penkala IJ, Liberti DC, Pankin J, Sivakumar A, Kremp MM, Jayachandran S, Katzen J, Leach JP, Windmueller R, Stolz K, Morley MP, Babu A, Zhou S, Frank DB, Morrisey EE. Penkala IJ, et al. Cell Stem Cell. 2021 Oct 7;28(10):1775-1789.e5. doi: 10.1016/j.stem.2021.04.026. Epub 2021 May 10. Cell Stem Cell. 2021. PMID: 33974915 Free PMC article.
Disruption of proteostasis causes IRE1 mediated reprogramming of alveolar epithelial cells.
Katzen J, Rodriguez L, Tomer Y, Babu A, Zhao M, Murthy A, Carson P, Barrett M, Basil MC, Carl J, Leach JP, Morley M, McGraw MD, Mulugeta S, Pelura T, Rosen G, Morrisey EE, Beers MF. Katzen J, et al. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2123187119. doi: 10.1073/pnas.2123187119. Epub 2022 Oct 17. Proc Natl Acad Sci U S A. 2022. PMID: 36252035 Free PMC article.
Microstructured Hydrogels to Guide Self-Assembly and Function of Lung Alveolospheres.
Loebel C, Weiner AI, Eiken MK, Katzen JB, Morley MP, Bala V, Cardenas-Diaz FL, Davidson MD, Shiraishi K, Basil MC, Ferguson LT, Spence JR, Ochs M, Beers MF, Morrisey EE, Vaughan AE, Burdick JA. Loebel C, et al. Adv Mater. 2022 Jul;34(28):e2202992. doi: 10.1002/adma.202202992. Epub 2022 Jun 7. Adv Mater. 2022. PMID: 35522531 Free PMC article.
The common ABCA3E292V variant disrupts AT2 cell quality control and increases susceptibility to lung injury and aberrant remodeling.
Tomer Y, Wambach J, Knudsen L, Zhao M, Rodriguez LR, Murthy A, White FV, Venosa A, Katzen J, Ochs M, Hamvas A, Beers MF, Mulugeta S. Tomer Y, et al. Am J Physiol Lung Cell Mol Physiol. 2021 Aug 1;321(2):L291-L307. doi: 10.1152/ajplung.00400.2020. Epub 2021 Jun 16. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34132118 Free PMC article.
Molecular Imaging in Precision-Cut Non-Small Cell Lung Cancer Slices.
Azari F, Kennedy GT, Chang A, Low P, Basil M, Planer J, Katzen J, Eruslanov E, Albelda S, Singhal S. Azari F, et al. Ann Thorac Surg. 2024 Feb;117(2):458-465. doi: 10.1016/j.athoracsur.2023.07.037. Epub 2023 Aug 10. Ann Thorac Surg. 2024. PMID: 37572959
15 results